Evidence map›Paper›PMID 40362619›Full record

ArticleInternational journal of molecular sciences2025

Rescue of the First Mitochondrial Membrane Carrier, the mPiC, by TAT-Mediated Protein Replacement Treatment.

Samar Zabit, Orly Melloul, Michal Lichtenstein, Erin L Seifert, Haya Lorberboum-Galski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samar ZabitDepartment of Biochemistry and Molecular Biology, The Institute for Medical Research Israel-Canada (IMRIC), Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9190501, Israel.
Orly MelloulDepartment of Biochemistry and Molecular Biology, The Institute for Medical Research Israel-Canada (IMRIC), Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9190501, Israel.
Michal LichtensteinDepartment of Biochemistry and Molecular Biology, The Institute for Medical Research Israel-Canada (IMRIC), Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9190501, Israel.
Erin L SeifertMitoCare Center, Department of Pathology and Genomic Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Haya Lorberboum-GalskiDepartment of Biochemistry and Molecular Biology, The Institute for Medical Research Israel-Canada (IMRIC), Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9190501, Israel.ORCID 0000-0002-2174-4346

Funding

USA, Department Of Defence W81XWH-17-1-0203
6 · The paper itself

Abstract

The mitochondrial phosphate carrier (mPiC), encoded by the nuclear gene

Indexed as

Mitochondrial MembranesMitochondrial Membrane Transport ProteinsPhosphate Transport ProteinsCopperHumansMitochondriaRecombinant Fusion ProteinsCopperMitochondrial Membrane Transport ProteinsPhosphate Transport ProteinsRecombinant Fusion Proteinsmitochondriamitochondrial phosphate carriermitochondrial phosphate carrier deficiency (MPCD)protein replacement treatmentTAT-mediated therapy

Identifiers

PMID40362619
PMCPMC12073058

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.