Evidence map›Paper›PMID 40362596›Full record

ReviewInternational journal of molecular sciences2025

Harnessing Azelaic Acid for Acute Myeloid Leukemia Treatment: A Novel Approach to Overcoming Chemoresistance and Improving Outcomes.

Silvia Di Agostino, Anna Di Vito, Annamaria Aloisio, Giovanna Lucia Piazzetta, Nadia Lobello, Jessica Bria, Emanuela Chiarella

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Silvia Di AgostinoDepartment of Health Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaroo, Italy.ORCID 0000-0003-3730-1125
Anna Di VitoDepartment of Clinical and Experimental Medicine, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-8294-8684
Annamaria AloisioDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Giovanna Lucia PiazzettaDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Nadia LobelloDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Jessica BriaDepartment of Clinical and Experimental Medicine, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Emanuela ChiarellaDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-8314-715X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Azelaic acid (AZA), an aliphatic dicarboxylic acid (HOOC-(CH2)

Indexed as

Antineoplastic AgentsDicarboxylic AcidsDrug Resistance, NeoplasmLeukemia, Myeloid, AcuteAnimalsApoptosisCell ProliferationHumansReactive Oxygen SpeciesAntineoplastic Agentsazelaic acidDicarboxylic AcidsReactive Oxygen Speciesacute myeloid leukemia (AML)apoptosisazelaic acid (AZA)Notch signalingreactive oxygen species (ROS)

Identifiers

PMID40362596
PMCPMC12073036

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.