Evidence map›Paper›PMID 40362562›Full record

ArticleInternational journal of molecular sciences2025

NAT10 Regulates LPS-Induced Inflammation via Stabilization of N4-Acetylated PTX3 mRNA in Human Dental Pulp Stem Cells.

Zihan Ni, Luhui Cai, I-Chen Tsai, Wenqian Ding, Cheng Tian, Di Li, Qiong Xu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zihan NiHospital of Stomatology, Sun Yat-sen University, 56# Lingyuan West Road, Guangzhou 510055, China.ORCID 0000-0002-1702-6050
Luhui CaiHospital of Stomatology, Sun Yat-sen University, 56# Lingyuan West Road, Guangzhou 510055, China.
I-Chen TsaiHospital of Stomatology, Sun Yat-sen University, 56# Lingyuan West Road, Guangzhou 510055, China.
Wenqian DingHospital of Stomatology, Sun Yat-sen University, 56# Lingyuan West Road, Guangzhou 510055, China.ORCID 0009-0007-5121-6628
Cheng TianHospital of Stomatology, Sun Yat-sen University, 56# Lingyuan West Road, Guangzhou 510055, China.
Di LiHospital of Stomatology, Sun Yat-sen University, 56# Lingyuan West Road, Guangzhou 510055, China.
Qiong XuHospital of Stomatology, Sun Yat-sen University, 56# Lingyuan West Road, Guangzhou 510055, China.ORCID 0000-0002-7448-6723

Funding

Guangdong Basic and Applied Basic Research Foundation No. 2024A1515013047National Natural Science Foundation of China No. 82370944, No. 82401087
6 · The paper itself

Abstract

Severe dental pulp inflammation can lead to tissue lysis and destruction, underscoring the necessity for effective treatment of pulpitis. N-acetyltransferase 10 (NAT10)-mediated N4-acetylcytidine (ac

Indexed as

AcetyltransferasesC-Reactive ProteinDental PulpInflammationPulpitisSerum Amyloid P-ComponentStem CellsAcetylationAnimalsHumansLipopolysaccharidesMalePentraxinsRatsReactive Oxygen SpeciesRNA, MessengerAcetyltransferasesC-Reactive ProteinLipopolysaccharidesPentraxinsReactive Oxygen SpeciesRNA, MessengerSerum Amyloid P-Componenthuman dental pulp stem cells (hDPSCs)inflammationlipopolysaccharide (LPS)N4-acetylcytidine (ac4C)N-acetyltransferase 10 (NAT10)pentraxins 3 (PTX3)

Identifiers

PMID40362562
PMCPMC12072506

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.