Evidence map›Paper›PMID 40362536›Full record

ArticleInternational journal of molecular sciences2025

Active Substances from the Micro-Immunotherapy Medicine 2LC1

Camille Jacques, Irene Marchesi, Francesco Paolo Fiorentino, Flora Marchand, Mathias Chatelais, Ilaria Floris

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Camille JacquesPreclinical Research Department, Labo'life France, Pescalis-Les Magnys, 79320 Moncoutant-sur-Sevre, France.ORCID 0000-0002-8044-0545
Irene MarchesiKitos Biotech s.r.l.s., Porto Conte Ricerche, S.P. 55 Porto Conte-Capo Caccia, Km 8,400 Loc. Tramariglio, 07041 Alghero, Italy.
Francesco Paolo FiorentinoKitos Biotech s.r.l.s., Porto Conte Ricerche, S.P. 55 Porto Conte-Capo Caccia, Km 8,400 Loc. Tramariglio, 07041 Alghero, Italy.
Flora MarchandProfileHIT, 7 Rue du Buisson, 44680 Sainte-Pazanne, France.
Mathias ChatelaisProfileHIT, 7 Rue du Buisson, 44680 Sainte-Pazanne, France.
Ilaria FlorisPreclinical Research Department, Labo'life France, Pescalis-Les Magnys, 79320 Moncoutant-sur-Sevre, France.ORCID 0000-0003-4089-3133

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor-associated macrophages (TAMs) play a pivotal role in cancer regulation by influencing tumor growth, metastasis, and the immune microenvironment. By providing low doses and ultra-low doses (ULD) of immune regulators to the organism, micro-immunotherapy (MI) medicines (MIM) could be seen as valuable adjuvant drugs in the context of a wide range of pathological conditions, including cancers. Thus, these MIM could target TAMs, affecting their phenotype and activities. In this study, the anti-tumor and the immune-stimulatory effects of four capsules out of the ten composing the Labo'life's MIM 2LC1

Indexed as

Antineoplastic AgentsBreast NeoplasmsColonic NeoplasmsImmunotherapyMacrophagesProstatic NeoplasmsCell Line, TumorFemaleHCT116 CellsHumansMaleTumor-Associated MacrophagesTumor MicroenvironmentAntineoplastic Agentscancer cells modelsC-MYClow dosesmacrophagesmicro-immunotherapyultra-low doses

Identifiers

PMID40362536
PMCPMC12072473

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.