Evidence map›Paper›PMID 40362459›Full record

ArticleInternational journal of molecular sciences2025

Hypervesiculation Meets Sec-Targeting: Enhancing Heterologous Protein Loading in

Ignacio Fuentes, Francisco Parra, Diego Rojas, Andrés Silva, Jan Nevermann, María Carolina Otero, Fernando Gil, Iván L Calderón, Juan A Fuentes

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Cytoplasmic membrane vesicles fromFrontiers in microbiology · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ignacio FuentesLaboratorio de Genética y Patogénesis Bacteriana, Centro de Investigación de Resiliencia a Pandemias, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370186, Chile.ORCID 0009-0005-2907-3080
Francisco ParraLaboratorio de Genética y Patogénesis Bacteriana, Centro de Investigación de Resiliencia a Pandemias, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370186, Chile.ORCID 0009-0004-1541-8968
Diego RojasLaboratorio de Genética y Patogénesis Bacteriana, Centro de Investigación de Resiliencia a Pandemias, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370186, Chile.
Andrés SilvaLaboratorio de Genética y Patogénesis Bacteriana, Centro de Investigación de Resiliencia a Pandemias, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370186, Chile.
Jan NevermannLaboratorio de Genética y Patogénesis Bacteriana, Centro de Investigación de Resiliencia a Pandemias, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370186, Chile.
María Carolina OteroEscuela de Química y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 7591538, Chile.ORCID 0000-0002-8608-9813
Fernando GilSchool of Medicine, Faculty of Medicine, Universidad de los Andes, Santiago 7620001, Chile.
Iván L CalderónLaboratorio de RNAs Bacterianos, Centro de Investigación de Resiliencia a Pandemias, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370186, Chile.ORCID 0000-0003-3554-0894
Juan A FuentesLaboratorio de Genética y Patogénesis Bacteriana, Centro de Investigación de Resiliencia a Pandemias, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370186, Chile.ORCID 0000-0002-9374-0707

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico 1220584
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial Outer Membrane ProteinsSalmonella typhiAnimalsBacterial ProteinsEpithelial CellsFemaleHumansImmunizationMiceProtein TransportTyphoid FeverBacterial Outer Membrane ProteinsBacterial ProteinsdegSheterologous protein loadinghypervesiculationimmunogenicitymCherrynanocarriersOMVsSalmonella TyphiSec-targetingtolR

Identifiers

PMID40362459
PMCPMC12072155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.