Evidence map›Paper›PMID 40362440›Full record

ArticleInternational journal of molecular sciences2025

Molecular Hydrogen Ameliorates Anti-Desmoglein 1 Antibody-Induced Pemphigus-Associated Interstitial Lung Disease by Inhibiting Oxidative Stress.

Chang Tang, Lanting Wang, Zihua Chen, Xiangguang Shi, Yahui Chen, Jin Yang, Haiqing Gao, Chenggong Guan, Shan He, Luyao Zhang and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Research Progress of Molecular HDrug design, development and therapy · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Chang TangDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Lanting WangDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Zihua ChenDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Xiangguang ShiDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Yahui ChenState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, and Human Phenome Institute, Fudan University, Shanghai 200437, China.ORCID 0009-0003-9797-429X
Jin YangDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Haiqing GaoDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Chenggong GuanDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Shan HeDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Luyao ZhangDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Shenyuan ZhengDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Fanping YangDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Sheng-An ChenDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Li MaDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Zhen ZhangDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Ying ZhaoDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Qingmei LiuDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Jiucun WangDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai 200437, China.
Xiaoqun LuoDepartment of Allergy & Immunology, Huashan Hospital, Fudan University, Shanghai 200437, China.ORCID 0000-0002-5345-6517

Funding

National Natural Science Foundation of China (NSFC) Grant No. 81872525 Grant No. 82173422 Grant No. 82270070Shanghai Shenkang Hospital Development Center Technical Standardization Management and Promotion Project Grant No. 30302149001the National Key Clinical Specialty Construction Project in 2021 Construction of a multidisciplinary treatment team for the Department of Allergy and Immu-nology at Huashan Hospital
6 · The paper itself

Abstract

Pemphigus-associated interstitial lung disease (P-ILD) is a severe complication observed in pemphigus patients that is characterized by pulmonary interstitial inflammation and fibrosis. This study investigated the role of anti-desmoglein (Dsg) 1/3 antibodies in P-ILD pathogenesis and evaluated the therapeutic potential of molecular hydrogen (H

Indexed as

AutoantibodiesDesmoglein 1HydrogenLung Diseases, InterstitialOxidative StressPemphigusAnimalsCytokinesDisease Models, AnimalMaleMiceMice, Inbred BALB CPulmonary FibrosisAutoantibodiesCytokinesDesmoglein 1Hydrogenanti-desmoglein 1 antibodyinterstitial lung diseasemolecular hydrogenoxidative stresspemphigus

Identifiers

PMID40362440
PMCPMC12071603

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.