Evidence map›Paper›PMID 40362387›Full record

ArticleInternational journal of molecular sciences2025

Antioxidant Peptide Production Using Keratin from Feather Waste: Effect of Extraction and Thiol Blocking Method.

Mehrnaz Sheikh Hosseini, Zahra Moosavi-Nejad, Fatemeh Rezaei Sadrabadi, Hamid Hosano

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mehrnaz Sheikh HosseiniDepartment of Biotechnology, Faculty of Biological Sciences, Alzahra University, Tehran 1993893973, Iran.ORCID 0000-0002-2884-8535
Zahra Moosavi-NejadDepartment of Biotechnology, Faculty of Biological Sciences, Alzahra University, Tehran 1993893973, Iran.ORCID 0000-0002-9112-0686
Fatemeh Rezaei SadrabadiDepartment of Biotechnology, Faculty of Biological Sciences, Alzahra University, Tehran 1993893973, Iran.
Hamid HosanoBiomaterials Department, Institute of Industrial Nanomaterials, Kumamoto University, Kumamoto 860-8555, Japan.ORCID 0000-0003-3886-6363

Funding

Alzahra University D03/3/2152
6 · The paper itself

Abstract

Keratin-made biomaterials, including feathers, are considered a protein-rich bioresource due to their intrinsic properties, including biocompatibility, biodegradability, mechanical resistance, and biological abundance. Beta-keratin exists as an insoluble stringy protein due to the high presence of disulfide cross-links, and as a result, it is mechanically stable and resistant to enzymatic digestion. Because of this, it is not easily decomposed, and this has made the application of feathers difficult. In this study, after dissolving feathers in NaOH, sodium sulfide, and 2-Mercaptoethanol (2-ME), the relative molecular mass of beta-keratin was calculated. Thin-layer chromatography was also used to display proteins with lower molecular weights. The antioxidant activities of the samples were evaluated by Fe-chelating and free radical scavenging tests with 2,2-diphenyl-1-picrylhydrazyl (DPPH). To investigate the effect of blocking thiol groups on the antioxidant activity of dissolved keratin, iodoacetamide and H

Indexed as

AntioxidantsFeathersKeratinsPeptidesSulfhydryl CompoundsAnimalsBiphenyl CompoundsChickensFree Radical ScavengersHydrogen PeroxidePicrates1,1-diphenyl-2-picrylhydrazylAntioxidantsBiphenyl CompoundsFree Radical ScavengersHydrogen PeroxideKeratinsPeptidesPicratesSulfhydryl Compoundsantioxidant activitydissolutionfeather keratinFe-chelatingradical scavengingthiol-blocking

Identifiers

PMID40362387
PMCPMC12071990

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.