Evidence map›Paper›PMID 40362366›Full record

ArticleInternational journal of molecular sciences2025

Long-Term Moderate Increase in Medium-Chain Fatty Acids Intake Enhances Muscle Metabolism and Function in Mice.

Ziwei Zhang, Cong Wu, Shuo Wang, Yishan Tong, Jiapeng Huang, Chuwen Xue, Tiehan Cao, Katsuhiko Suzuki

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziwei ZhangGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.ORCID 0009-0000-6669-8737
Cong WuGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.ORCID 0009-0009-1975-0809
Shuo WangGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.ORCID 0009-0002-0162-6374
Yishan TongGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.ORCID 0009-0006-9671-0219
Jiapeng HuangGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.ORCID 0000-0003-3969-3708
Chuwen XueGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.ORCID 0009-0004-0906-5481
Tiehan CaoGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.
Katsuhiko SuzukiFaculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.ORCID 0000-0002-6572-5809

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medium-chain fatty acids (MCFAs) refer to a mixture of fatty acids typically composed of 6 to 12 carbon atoms. The unique transport and rapid metabolism of MCFAs provide more clinical benefits than other substrates, such as long-chain fatty acids. Although many studies have shown that MCFAs may improve exercise capacity and muscle strength, applications have mainly been limited to low doses. This study explores the effects of high-dose MCFA intake on muscle strength and exercise endurance. Mice were fed high-fat diets containing 30, 35, and 40% (

Indexed as

Fatty AcidsMuscle, SkeletalAnimalsDiet, High-FatMaleMiceMice, Inbred C57BLMuscle StrengthMuscular AtrophyPhysical Conditioning, AnimalPhysical EnduranceFatty Acidsexercise tolerancegrip strengthmedium-chain fatty acidsmuscle differentiationmuscle regenerationprotein catabolism

Identifiers

PMID40362366
PMCPMC12071283

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.