Evidence map›Paper›PMID 40362338›Full record

ArticleInternational journal of molecular sciences2025

Oleanolic Acid Lactones as Effective Agents in the Combat with Cancers-Cytotoxic and Antioxidant Activity, SAR Analysis, Molecular Docking and ADMETox Profile.

Barbara Bednarczyk-Cwynar, Andrzej Günther, Piotr Ruszkowski, Szymon Sip, Przemysław Zalewski

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Barbara Bednarczyk-CwynarDepartment of Organic Chemistry, Faculty of Pharmacy, Poznan University of Medical Sciences, Collegium Pharmaceuticum 2 (CP.2), Rokietnicka Str. 3, 60-806 Poznan, Poland.ORCID 0000-0003-2958-9106
Andrzej GüntherDepartment of Organic Chemistry, Faculty of Pharmacy, Poznan University of Medical Sciences, Collegium Pharmaceuticum 2 (CP.2), Rokietnicka Str. 3, 60-806 Poznan, Poland.ORCID 0000-0002-4492-6329
Piotr RuszkowskiDepartment of Pharmacology, Faculty of Pharmacy, Poznan University of Medical Sciences, Collegium Pharmaceuticum 1 (CP.1), Rokietnicka Str. 3, 60-806 Poznan, Poland.ORCID 0000-0002-5106-8510
Szymon SipDepartment of Pharmacognosy and Biomaterials, Faculty of Pharmacy, Poznan University of Medical Sciences, Collegium Pharmaceuticum 1 (CP.1), Rokietnicka Str. 3, 60-806 Poznan, Poland.ORCID 0000-0002-6618-9956
Przemysław ZalewskiDepartment of Pharmacognosy and Biomaterials, Faculty of Pharmacy, Poznan University of Medical Sciences, Collegium Pharmaceuticum 1 (CP.1), Rokietnicka Str. 3, 60-806 Poznan, Poland.ORCID 0000-0002-5116-9426

Funding

Poznan University of Medical Sciences
6 · The paper itself

Abstract

Oleanolic acid derivatives, specifically lactones (

Indexed as

Antineoplastic AgentsAntioxidantsLactonesNeoplasmsOleanolic AcidCell Line, TumorErbB ReceptorsHumansMolecular Docking SimulationStructure-Activity RelationshipAntineoplastic AgentsAntioxidantsErbB ReceptorsLactonesOleanolic AcidADMEToxantioxidant activityantioxidant activity of triterpenescytotoxic activitycytotoxic activity of triterpenesmolecular dockingnatural productsnatural products’ modificationsoleanolic acidoleanolic acid lactonesSARtriterpene lactonestriterpenes

Identifiers

PMID40362338
PMCPMC12072072

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.