Evidence map›Paper›PMID 40362239›Full record

Trial reportInternational journal of molecular sciences2025

Skin Photoprotection and Anti-Aging Benefits of a Combination of Rosemary and Grapefruit Extracts: Evidence from In Vitro Models and Human Study.

Pau Navarro, Julián Castillo, Jonathan Jones, Adrián García, Nuria Caturla

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Unlocking the Potential ofFoods (Basel, Switzerland) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pau NavarroResearch and Development Department, Monteloeder SL, Miguel Servet 16, 03203 Elche, Spain.
Julián CastilloFood Technology & Nutritional Department, Universidad Católica San Antonio de Murcia (UCAM), Campus de los Jerónimos, Carretera Guadalupe, 30107 Murcia, Spain.
Jonathan JonesResearch and Development Department, Monteloeder SL, Miguel Servet 16, 03203 Elche, Spain.
Adrián GarcíaResearch and Development Department, Monteloeder SL, Miguel Servet 16, 03203 Elche, Spain.ORCID 0009-0006-6134-1556
Nuria CaturlaResearch and Development Department, Monteloeder SL, Miguel Servet 16, 03203 Elche, Spain.ORCID 0000-0003-3464-0594

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin exposure to ultraviolet radiation (UVR) causes oxidative stress, inflammation, and collagen degradation and can trigger erythema. While topical formulas protect the skin from UV damage, there is growing evidence that certain botanical ingredients taken orally may have an added benefit. This study evaluated the photoprotective, anti-photoaging, and anti-erythema efficacy of a combination of rosemary and grapefruit extract (Nutroxsun

Indexed as

Citrus paradisiPlant ExtractsRosmarinusSkinSkin AgingAdultCell LineCross-Over StudiesElastinErythemaFemaleFibroblastsHumansKeratinocytesMaleMatrix Metalloproteinase 1ElastinMatrix Metalloproteinase 1Matrix Metalloproteinase 3Plant ExtractsReactive Oxygen SpeciesCitrus paradisicollagendietary supplementelastinerythemametalloproteinases and clinical studyphotoagingphotoprotectionRosmarinus officinalis

Identifiers

PMID40362239
PMCPMC12071866

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.