Evidence map›Paper›PMID 40362203›Full record

ArticleInternational journal of molecular sciences2025

Extracellular Vesicle Abundance, but Not a High Aggregation-Prone Peptide Cargo, Is Associated with Dihydroartemisinin Exposure in

Kwesi Z Tandoh, Yunuen Avalos-Padilla, Prince Ameyaw, Elisabeth K Laryea-Akrong, Gordon A Awandare, Michael David Wilson, Neils B Quashie, Xavier Fernàndez-Busquets, Nancy O Duah-Quashie

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kwesi Z TandohWest African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Legon, Accra P.O. Box LG 54, Ghana.ORCID 0000-0002-1628-2845
Yunuen Avalos-PadillaInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona, Spain.ORCID 0000-0003-4074-5624
Prince AmeyawDepartment of Epidemiology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra P.O. Box LG 54, Ghana.
Elisabeth K Laryea-AkrongWest African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Legon, Accra P.O. Box LG 54, Ghana.
Gordon A AwandareWest African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Legon, Accra P.O. Box LG 54, Ghana.
Michael David WilsonDepartment of Parasitology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra P.O. Box LG 54, Ghana.ORCID 0000-0002-6048-8509
Neils B QuashieWest African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Legon, Accra P.O. Box LG 54, Ghana.
Xavier Fernàndez-BusquetsInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona, Spain.ORCID 0000-0002-4622-9631
Nancy O Duah-QuashieWest African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Legon, Accra P.O. Box LG 54, Ghana.ORCID 0000-0001-8819-1793

Funding

PhD fellowship from PhD fellowship from Building a New Generation of Academics (BANGA Africa, University of Ghana and Carnegie Corporation of New York); and WACCBIP-World Bank ACE PhD fellowship (WACCBIP+NCDs: Awandare) PhD fellowship from PhD fellowship from Building a New Generation of Academics (BANGA Africa, University of Ghana and Carnegie Corporation of New York); and WACCBIP-World Bank ACE PhD fellowship (WACCBIP+NCDs: Awandare)
6 · The paper itself

Abstract

Our understanding of the molecular mechanisms undergirding artemisinin (ART) resistance in

Indexed as

AntimalarialsArtemisininsExtracellular VesiclesPeptidesPlasmodium falciparumDrug ResistanceHumansMalaria, FalciparumProtozoan ProteinsAntimalarialsArtemisininsartenimolPeptidesProtozoan Proteinsaggregated proteinsartemisinin resistancedihydroartemisinin exposureEV exports hypothesisextracellular vesicles abundancePlasmodium falciparum

Identifiers

PMID40362203
PMCPMC12072043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.