Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
13 authors.
Theresa LehenauerUniversity Children's Hospital, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.
Heidi Jaksch-BogenspergerDepartment of Obstetrics and Gynaecology, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.
Sara HuberResearch Program for Receptor Biochemistry and Tumor Metabolism, University Children's Hospital, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.ORCID 0000-0003-3589-4924
Daniel WeghuberUniversity Children's Hospital, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.ORCID 0000-0002-4389-0379
Thorsten FischerDepartment of Obstetrics and Gynaecology, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.
Johannes A MayrUniversity Children's Hospital, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.ORCID 0000-0001-6970-336X
Barbara KoflerResearch Program for Receptor Biochemistry and Tumor Metabolism, University Children's Hospital, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.ORCID 0000-0002-1198-4776
Bettina NeumayerDepartment of Pathology, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.
Daniel GharehbaghiDepartment of Obstetrics and Gynaecology, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.
Michaela Duggan-PeerDepartment of Obstetrics and Gynaecology, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.
Maximilian BrandstetterDepartment of Obstetrics and Gynaecology, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.ORCID 0000-0003-3542-7285
Claudius FazelniaDepartment of Obstetrics and Gynaecology, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.
René G FeichtingerUniversity Children's Hospital, Salzburger Landesklinken (SALK) and Paracelsus Medical University (PMU), Müllner Hauptstraße 48, 5020 Salzburg, Austria.ORCID 0000-0002-4215-8258
Funding
Paracelsus Medical University 2022-SEED-018
6 · The paper itself
Abstract
Preeclampsia (PE), a pregnancy complication characterized by high blood pressure and organ damage, has been suggested to be associated with mitochondrial dysfunction, although evidence remains limited. This study aimed to investigate the activity of oxidative phosphorylation (OXPHOS) enzymes and the expression of related proteins in placental tissues from women diagnosed with early-onset preeclampsia (eoPE, <34 weeks of gestation), late-onset preeclampsia (loPE, ≥34 weeks of gestation), and normotensive controls. Placental samples were analyzed using immunohistochemistry, western blotting, and enzymatic activity assays to assess the activity and expression of OXPHOS complexes. Complex I activity was increased by 80% in eoPE and 56% in loPE, with positive correlations between normalized complex I expression, gestational age at delivery (r = 0.85,
Indexed as
MitochondriaOxidative PhosphorylationPlacentaPre-EclampsiaAdultCase-Control StudiesElectron Transport Complex IElectron Transport Complex IVFemaleGestational AgeHumansPregnancyElectron Transport Complex IElectron Transport Complex IVmitochondriaoxidative phosphorylationplacentapreeclampsia
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Mitochondrial Oxidative Phosphorylation Alterations in Placental Tissues from Early- and Late-Onset Preeclampsia. · full record | OpenQuestion