ArticleAnimals : an open access journal from MDPI2025
The Novel Antigenic Epitopes of African Swine Fever Virus Inner Membrane p54 Protein Revealed by Monoclonal Antibodies.
Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Novel Linear B Cell Epitopes of ASFV p54: Screening and Fine-Scale Mapping.Microorganisms · 2026Article
- Host-pathogen interactions in African swine fever: From viral entry to systemic disease progression.Cell insight · 2026Review
- Subtle Genetic Shifts of African Swine Fever Virus Among Vietnamese Domestic Swine Following Live-Attenuated Vaccine Commercialization.Transboundary and emerging diseases · 2026Article
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Authors and funding
12 authors.
Funding
Abstract
African swine fever (ASF) is caused by the African swine fever virus (ASFV); infection in domestic pigs and wild boars leads to a highly contagious, hemorrhagic disease. The p54 protein is encoded by the ASFV E183L gene and is an important structural protein located on the inner envelope of the virus. It is involved in processes of virus assembly, apoptosis induction, and neutralizing antibody production. In this study, three specific monoclonal antibodies (mAbs) against ASFV p54 protein were generated, namely 6B11, 3E3, and 3C10, from mice who were immunized with recombinant prokaryotic p54-truncated protein. Three novel linear B cell epitopes, recognized by the mAbs, were revealed:
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