Evidence map›Paper›PMID 40362093›Full record

ArticleAnimals : an open access journal from MDPI2025

Red Blood Cell Transcriptome Reflects Physiological Responses to Alternative Nutrient Sources in Gilthead Seabream (

Rafael Angelakopoulos, Andreas Tsipourlianos, Alexia E Fytsili, Leonidas Papaharisis, Arkadios Dimitroglou, Dimitrios Barkas, Zissis Mamuris, Themistoklis Giannoulis, Katerina A Moutou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rafael AngelakopoulosLaboratory of Genetics, Comparative and Evolutionary Biology, Department of Biochemistry and Biotechnology, University of Thessaly, Biopolis, 41500 Larissa, Greece.ORCID 0000-0002-2354-2019
Andreas TsipourlianosLaboratory of Genetics, Comparative and Evolutionary Biology, Department of Biochemistry and Biotechnology, University of Thessaly, Biopolis, 41500 Larissa, Greece.ORCID 0009-0000-4964-557X
Alexia E FytsiliLaboratory of Genetics, Comparative and Evolutionary Biology, Department of Biochemistry and Biotechnology, University of Thessaly, Biopolis, 41500 Larissa, Greece.
Leonidas PapaharisisAvramar Aquaculture SA, 19002 Athens, Greece.ORCID 0009-0003-0840-7358
Arkadios DimitroglouAvramar Aquaculture SA, 19002 Athens, Greece.ORCID 0000-0002-6136-8226
Dimitrios BarkasAvramar Aquaculture SA, 19002 Athens, Greece.
Zissis MamurisLaboratory of Genetics, Comparative and Evolutionary Biology, Department of Biochemistry and Biotechnology, University of Thessaly, Biopolis, 41500 Larissa, Greece.ORCID 0000-0002-6868-8927
Themistoklis GiannoulisLaboratory of Biology, Genetics and Bioinformatics, Department of Animal Science, University of Thessaly, Greece Gaiopolis, 41334 Larissa, Greece.ORCID 0000-0002-1842-5432
Katerina A MoutouLaboratory of Genetics, Comparative and Evolutionary Biology, Department of Biochemistry and Biotechnology, University of Thessaly, Biopolis, 41500 Larissa, Greece.ORCID 0000-0002-6429-3776

Funding

This research was co-financed by Greece, Hellenic Ministry of Rural Development and Food, and the European Union, European Maritime and Fisheries Fund in the context of the implementation of the Greek Operational Program for Fisheries, Priority Axis "Inno MIS 5010669
6 · The paper itself

Abstract

The sustainable growth of finfish farming relies heavily on reducing the high ecological footprint of sourcing and producing fish feeds that accounts for almost 50% of the total ecological footprint of finfish farming. Sustainable alternatives to fishmeal often pose challenges due to the presence of antinutritional factors and nutrient imbalances that impair fish health and growth. Screening for alternative nutrient sources and adapting to global commodity fluctuations requires modern tools that can predict the physiological responses of fish early and reliably. The present study explores for the first time the potential of fish red blood cell (RBC) transcriptome as a minimally invasive biomarker of physiological responses in gilthead seabream (

Indexed as

fishmeal alternativesgilthead seabreamminimally invasive sample collectionphysiological responsessustainable aquaculturetranscriptome analysis

Identifiers

PMID40362093
PMCPMC12070918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.