ArticleAnimals : an open access journal from MDPI2025
Weaning as Stressor for Calf Welfare.
Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Composite probiotics improve growth performance and enhance immune and antioxidant capacity in weaned yaks by modulating rumen microbiota and their metabolites.BMC microbiology · 2026Article
- Unfamiliar Handler-Induced Hypercortisolism, Abnormal Oral Behaviors, and Delayed Inflammatory Response in Pre-Weaned Zebu Cross Calves.Animals : an open access journal from MDPI · 2026Article
- Effect of growth-promoting implants and revaccination timing on stress physiology and growth performance in male beef calves.Translational animal science · 2026Article
- Circulating leukocyte gene expression responses to weaning and their association with growth in holstein calves.PloS one · 2026Article
- Impacts of Maternal Bovine Appeasing Substance Administered at Weaning on Behavioral and Physiological Adaptation of Beef Heifers to the Feedlot.Animals : an open access journal from MDPI · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Weaning is a critical period for calves, affecting their well-being, health, and productivity. The present study analyzed 61 calves to evaluate the effects of weaning as a stress factor by monitoring hematological, biochemical, and immune parameters. Blood samples were collected at the start of weaning at 130-135 days (T0), 3 (T1) and 7 (T2) days later, and finally at 150 days of age. The results showed changes in the levels of cortisol, inflammatory cytokines (TNF-α, INF-γ and IL-8) and acute-phase proteins. Alterations in white blood cells were also observed, such as neutrophilia and lymphopenia, which are typical signs of an adverse stress response. Biochemically, the switch from milk to solid food caused imbalances in protein, cholesterol, and triglyceride levels, indicating a relevant metabolic adaptation. Serum electrophoresis showed a decrease in albumin and an increase in γ-globulins, a sign of immune maturation. The results suggest that weaning is one of the most important stressors for calves, with both physiological and immune effects. However, this practice is necessary for breeding productivity. Future research could investigate the role of genetics and environment in weaning resilience to further optimize breeding practices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.