Evidence map›Paper›PMID 40362054›Full record

ArticleAnimals : an open access journal from MDPI2025

Serum Amyloid A Concentrations in Young Japanese Black Cattle: Relationship with Colostrum Intake and Establishing Cut-Off Concentrations.

Urara Shinya, Osamu Yamato, Yuka Iwamura, Tomohiro Kato, Yuhei Hamada, Oky Setyo Widodo, Masayasu Taniguchi, Mitsuhiro Takagi

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Urara ShinyaSoo Veterinary Clinic, Kagoshima A.M.A.A., Soo 899-8242, Japan.
Osamu YamatoJoint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan.ORCID 0000-0002-4430-5645
Yuka IwamuraSoo Veterinary Clinic, Kagoshima A.M.A.A., Soo 899-8242, Japan.
Tomohiro KatoSoo Veterinary Clinic, Kagoshima A.M.A.A., Soo 899-8242, Japan.
Yuhei HamadaSoo Veterinary Clinic, Kagoshima A.M.A.A., Soo 899-8242, Japan.
Oky Setyo WidodoDivision of Animal Husbandry, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya 60115, Indonesia.ORCID 0000-0002-0073-1394
Masayasu TaniguchiJoint Graduate School of Veterinary Sciences, Yamaguchi University, Yamaguchi 753-8515, Japan.ORCID 0000-0003-3422-1904
Mitsuhiro TakagiDivision of Animal Husbandry, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya 60115, Indonesia.

Funding

Japan Racing Association R3-no. 18
6 · The paper itself

Abstract

This study aimed to investigate the variations in serum amyloid A (SAA) concentrations and influencing factors in young Japanese Black (JB) cattle. The cut-off values were 18.5 mg/L, 17.7 mg/L, 14.4 mg/L, and 8.1 mg/L at 30-59, 60-89, 90-119, and 120-300 days of age, respectively. Calves that ingested colostrum had significantly higher SAA concentrations than those that did not. The SAA concentrations at 1-7 days of age showed no correlation with γ-glutamyltransferase, total protein, or globulin levels. A slight increase in mammary-associated amyloid A concentrations-a colostrum-derived SAA-was observed before and after colostrum intake on 1 day of age; however, a significant overall increase in SAA concentrations was noted. The reference values for the SAA concentration in 1-month-old calves also showed a gradual decline. These findings suggest that the elevated SAA concentrations in 1-month-old JB calves, similar to Holstein calves, are not due to absorption from colostrum but SAA is instead biosynthesized by the calves as a biological defense mechanism. The clinical application of SAA concentrations in JB calves after one month of age may contribute to improving calf productivity.

Indexed as

colostrumhealth careJapanese Black calvesmammary-associated amyloid Aserum amyloid A

Identifiers

PMID40362054
PMCPMC12070993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.