Evidence map›Paper›PMID 40361916›Full record

ArticleDiagnostics (Basel, Switzerland)2025

A Breast Cancer Polygenic Risk Score Validation in 15,490 Brazilians Using Exome Sequencing.

Flávia Eichemberger Rius, Rodrigo Santa Cruz Guindalini, Danilo Viana, Júlia Salomão, Laila Gallo, Renata Freitas, Cláudia Bertolacini, Lucas Taniguti, Danilo Imparato, Flávia Antunes and 14 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Flávia Eichemberger RiusMendelics, Sao Paulo 02511-000, SP, Brazil.
Rodrigo Santa Cruz GuindaliniInstituto D'Or de Pesquisa e Ensino (IDOR), Sao Paulo 01401-002, SP, Brazil.
Danilo VianaMendelics, Sao Paulo 02511-000, SP, Brazil.
Júlia SalomãoMendelics, Sao Paulo 02511-000, SP, Brazil.
Laila GalloMendelics, Sao Paulo 02511-000, SP, Brazil.
Renata FreitasMendelics, Sao Paulo 02511-000, SP, Brazil.
Cláudia BertolaciniMendelics, Sao Paulo 02511-000, SP, Brazil.
Lucas TanigutiMendelics, Sao Paulo 02511-000, SP, Brazil.ORCID 0000-0002-2682-7343
Danilo ImparatoMendelics, Sao Paulo 02511-000, SP, Brazil.ORCID 0000-0001-6979-4951
Flávia AntunesMendelics, Sao Paulo 02511-000, SP, Brazil.
Gabriel SousaMendelics, Sao Paulo 02511-000, SP, Brazil.
Renan AchjianMendelics, Sao Paulo 02511-000, SP, Brazil.
Eric FukuyamaMendelics, Sao Paulo 02511-000, SP, Brazil.
Cleandra GregórioMendelics, Sao Paulo 02511-000, SP, Brazil.ORCID 0000-0002-6476-219X
Iuri VenturaMendelics, Sao Paulo 02511-000, SP, Brazil.
Juliana GomesMendelics, Sao Paulo 02511-000, SP, Brazil.
Nathália TanigutiMendelics, Sao Paulo 02511-000, SP, Brazil.ORCID 0000-0001-8804-8380
Simone MaistroComprehensive Center for Precision Oncology (C2PO), Centro de Investigação Translacional em Oncologia (CTO), Departamento de Radiologia e Oncologia, Instituto do Cancer do Estado de Sao Paulo (ICESP), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 01246-000, SP, Brazil.ORCID 0000-0002-0937-2391
José Eduardo KriegerInstituto do Coração, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo (FMUSP), Sao Paulo 05403-900, SP, Brazil.ORCID 0000-0001-5464-1792
Yonglan ZhengMedicine and Human Genetics, Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, IL 60637, USA.
Dezheng HuoDepartment of Public Health Sciences, University of Chicago, Chicago, IL 60637, USA.
Olufunmilayo I OlopadeMedicine and Human Genetics, Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, IL 60637, USA.
Maria Aparecida Azevedo Koike FolgueiraComprehensive Center for Precision Oncology (C2PO), Centro de Investigação Translacional em Oncologia (CTO), Departamento de Radiologia e Oncologia, Instituto do Cancer do Estado de Sao Paulo (ICESP), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 01246-000, SP, Brazil.
David SchlesingerMendelics, Sao Paulo 02511-000, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

admixed populationbreast cancercancer geneticsnext-generation sequencing (NGS)polygenic risk score (PRS)precision medicine

Identifiers

PMID40361916
PMCPMC12071591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.