Engineering Baker's Yeast for Efficient cAMP Synthesis via Regulation of PKA Activity.

Xiaomeng Fu, Kunqiang Hong

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Global impact on metabolic capacity of yeast cell factories by optogenetic control of the cAMP-PKA axis.Applied and environmental microbiology · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xiaomeng FuCollege of Food Science and Technology, Wuhan Business University, Wuhan 430056, China.

Kunqiang HongCollege of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, China.

Funding

National Natural Science Foundation of China 32401228Open Research Fund of the Key Laboratory of Edible Oil Quality and Safety, State Administration for Market Regulation SYYKF202308Research Funding of Wuhan Polytechnic University 2023RZ081

6 · The paper itself

Abstract

cAMP (cyclic adenosine-3',5'-monophosphate) has extensive physiological functions and nutritional value for living organisms, and it regulates cellular metabolism mainly by modulating PKA (protein kinase A) activity. The current yields of cAMP synthesized by microbial fermentation are still low, which is arousing interest in developing high-yield cAMP strains. In this work, two baker's yeasts with high cAMP content were constructed by knocking out

Indexed as

BCY1cAMPnutritional yeastPKA activitypromoter truncationTPK

Identifiers

PMID40361616

DOI10.3390/foods14091533

PMCPMC12071475

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.