Evidence map›Paper›PMID 40361514›Full record

ReviewCancers2025

Geriatric Assessment and Management, Prehabilitation and Rehabilitation for Older Aldults with Non-Colorectal Digestive Cancers.

Amélie Aregui, Janina Estrada, Madeleine Lefèvre, Anna Carteaux-Taieb, Geoffroy Beraud-Chaulet, Pascal Hammel, Virginie Fossey-Diaz, Thomas Aparicio

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amélie AreguiParis Nord Oncogeriatrics Coordination Unit, Bretonneau and Saint Louis Hospitals, AP-HP, 75018 Paris, France.
Janina EstradaGeriatric Out-Patient Unit, Bretonneau Hospital, AP-HP, 75018 Paris, France.
Madeleine LefèvreParis Nord Oncogeriatrics Coordination Unit, Bretonneau and Saint Louis Hospitals, AP-HP, 75018 Paris, France.
Anna Carteaux-TaiebDepartment of Digestive and Endocrine Surgery, Saint-Louis Hospital, AP-HP, 75010 Paris, France.ORCID 0009-0000-0924-6646
Geoffroy Beraud-ChauletGeriatrics Departement, Paul Brousse Hospital, AP-HP, 94800 Villejuif, France.
Pascal HammelMedical Oncology Department, Paul Brousse Hospital, AP-HP, Université Paris Saclay, 94800 Villejuif, France.
Virginie Fossey-DiazParis Nord Oncogeriatrics Coordination Unit, Bretonneau and Saint Louis Hospitals, AP-HP, 75018 Paris, France.
Thomas AparicioGastroenterology Department, Saint Louis Hospital, AP-HP, Université Paris Cité, 75010 Paris, France.ORCID 0000-0001-8834-6927

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of cancer in older patients is high, reaching 2.3 million world-wide in 2018 for patients aged over 80. Because the characteristics of this population make therapeutic choices difficult, co-management between geriatricians and other cancer specialists has gradually become essential.

methodsThis narrative review aims to synthesize current data on the contribution of geriatric assessment in the management of elderly patients with non-colorectal digestive cancers. Oncogeriatric assessment is multi-domain, including the evaluation of co-morbidities, autonomy, nutrition, cognition, mood, and functional assessment.

resultsOncogeriatric parameters are predictive of mortality and adverse events. In the peri-operative phase of non-colorectal digestive cancer surgical management, geriatric management can assist in the decision-making process, identify frailties, and arrange a specific and personalized trimodal preoperative rehabilitation program, including nutritional management, adapted physical activity, and psychological care. Its aim is to limit the risks of confusion and of decompensation of comorbidities, mainly cardio-respiratory, which is associated with the highest morbidity in biliary-pancreatic surgery for older adults, facilitate recovery of previous autonomy when possible, and shorten hospital stay. For metastatic cancers, or during multimodal management, such as peri-operative chemotherapy for localized gastric cancers or pre-operative radio-chemotherapy for oesophageal or rectal cancers, specific assessment of the tolerance of chemotherapy is necessary. Neuropathic toxicity and chemobrain have a greater impact on elderly patients, with an increased loss of autonomy. Joint geriatric management can reduce the rate of grade 3-5 adverse effects of chemotherapy in particular and improve quality of life.

conclusionsCo-management between geriatricians and other specialties should be encouraged wherever possible.

Indexed as

geriatric comprehensive assessmentnon-colorectal digestive cancerolder adultsquality of lifetreatment tolerance

Identifiers

PMID40361514
PMCPMC12071841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.