Evidence map›Paper›PMID 40361484›Full record

ArticleCancers2025

Five Cellular Genes as Candidates for Cervical Adenocarcinoma Molecular Markers.

Isui Abril García-Montoya, Karla Berenice López-Córdova, Daniel Marrero-Rodríguez, Mauricio Salcedo-Vargas, Claudia Lucía Vargas-Requena, Angélica Maria Escárcega-Avila, Santos Adriana Martel-Estrada, Florinda Jiménez-Vega

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Isui Abril García-MontoyaInstituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Av. Plutarco Elías Calles #1210 Fovissste Chamizal, Ciudad Juárez 32310, Mexico.
Karla Berenice López-CórdovaInstituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Av. Plutarco Elías Calles #1210 Fovissste Chamizal, Ciudad Juárez 32310, Mexico.
Daniel Marrero-RodríguezUnidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México City 06720, Mexico.ORCID 0000-0001-5311-6654
Mauricio Salcedo-VargasUnidad de Investigación Biomédica y Oncológica Genómica, Hospital de Gineco Pediatría 3 A, OOAD CDMX Norte, Instituto Mexicano del Seguro Social, México City 07760, Mexico.
Claudia Lucía Vargas-RequenaInstituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Av. Plutarco Elías Calles #1210 Fovissste Chamizal, Ciudad Juárez 32310, Mexico.ORCID 0000-0001-7612-1616
Angélica Maria Escárcega-AvilaInstituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Av. Plutarco Elías Calles #1210 Fovissste Chamizal, Ciudad Juárez 32310, Mexico.ORCID 0000-0002-4066-0586
Santos Adriana Martel-EstradaDepartamento de Diseño, Instituto de Arquitectura, Diseño y Arte, Universidad Autonoma de Ciudad Juárez, Ciudad Juárez 32310, Mexico.
Florinda Jiménez-VegaInstituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Av. Plutarco Elías Calles #1210 Fovissste Chamizal, Ciudad Juárez 32310, Mexico.ORCID 0000-0003-3180-9104

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimCervical adenocarcinoma associated with Human Papillomavirus (HPV) infection represents 85-90% of all adenocarcinomas that have poor prognostic factors and is an important health public concern. Currently, cervical adenocarcinoma molecular markers are scarce. This study searched databases and the literature regarding candidate genes to find these molecular markers, which were experimentally evaluated in fresh cervical samples. MATERIALS AND

methodsBioinformatic analysis of 161 transcriptomic libraries of cervical tissues with or without lesions from the NCBI database was performed using the Partek Genomics Suite 6.6v software. The selected genes with a

resultsInitially, twenty-five genes were identified using bioinformatic analysis, and their expression was evaluated. The results showed that the

conclusionsThis five-gene panel could serve as a novel molecular tool for HPV-associated cervical adenocarcinoma detection.

Indexed as

BCL2cervical adenocarcinomaE6/E7genetic expressionHOXC8MACC1molecular markersRARβ

Identifiers

PMID40361484
PMCPMC12071559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.