ArticleCancers2025
Fatigue Level Associated with Quality of Life for Prostate Cancer Patients: Results from the All of Us Research Program.
Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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6 authors.
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Abstract
BACKGROUND/
objectivesProstate cancer (PCa) patients frequently experience extended survivorship, highlighting the importance of quality of life (QoL) in cancer care. QoL has been shown to influence survival and PCa progression. For PCa patients, fatigue is a common issue due to cancer itself or its treatments. However, many QoL studies on PCa patients are limited by small sample sizes in clinic settings and often overlook the impact of fatigue and health-related behaviors. To fill this gap, this study aims to evaluate fatigue associated with QoL and related health measures among PCa patients.
methodsThis study used the All of Us cohort with 6426 PCa patients. Factors associated with QoL and health outcomes were tested using logistic models.
resultsAmong PCa patients, 8.8% reported poor QoL, 20.9% reported poor physical health, and 9.0% reported poor mental health. Around 24.5% and 5.0% of PCa patients had a moderate and high fatigue level, respectively. A high fatigue level was significantly associated with poor QoL (OR = 2.33,
conclusionsThis study provides valuable insights about fatigue's important role in QoL, physical health, and mental health for PCa patients. Effective fatigue management is suggested to enhance QoL and overall well-being for PCa patients.
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