Evidence map›Paper›PMID 40361381›Full record

ArticleCancers2025

Development and Potent Anti-Tumor Activity of a Fully Humanized Anti-TAG-72-IL-2 Fusion Protein for Therapy of Solid Tumors.

Eric Aniogo, Lindsay Williams, Teresa Hong, Patty Wong, Susanta K Hui, Hemendra Ghimire, Erasmus K Poku, David M Colcher, Paul J Yazaki, John E Shively and 1 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eric AniogoDepartment of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.ORCID 0000-0001-6951-2977
Lindsay WilliamsDepartment of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.
Teresa HongDepartment of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.
Patty WongDepartment of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.
Susanta K HuiDepartment of Radiation Oncology, Beckman Research Institute and Medical Center, City of Hope, Duarte, CA 91010, USA.
Hemendra GhimireDepartment of Radiation Oncology, Beckman Research Institute and Medical Center, City of Hope, Duarte, CA 91010, USA.ORCID 0009-0009-9097-8662
Erasmus K PokuRadiopharmacy, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.
David M ColcherDepartment of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.ORCID 0000-0001-6647-2850
Paul J YazakiDepartment of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.ORCID 0000-0003-2626-3303
John E ShivelyDepartment of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.ORCID 0000-0002-7763-770X
Maciej KujawskiDepartment of Immunology and Theranostics, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.ORCID 0000-0002-9701-5211

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI John Charles Williams · 1985 to 2026
$86.3M
Targeted radiation and immunocytokine therapy for CEA positive malignanciesR01CA283603 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI John Ernest Shively, JEFFREY Y WONG · 2023 to 2026
$2.7M
NCI NIH HHS P30CA033572NCI NIH HHS R01 CA283603
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

breast cancercolon cancerfusion proteinsimmunotherapyradiation therapyTAG-72

Identifiers

PMID40361381
PMCPMC12071099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.