Evidence map›Paper›PMID 40361351›Full record

ArticleCancers2025

Comparison of the Hematotoxicity of PRRT with Lutathera

Markus Hofmann, Sophie C Kunte, Marcus Unterrainer, Astrid Delker, Adrien Holzgreve, Johannes Toms, Franz Joseph Gildehaus, Christoph J Auernhammer, Christine Spitzweg, Mathias J Zacherl and 4 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Markus HofmannDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Sophie C KunteDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0009-0003-3175-952X
Marcus UnterrainerDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Astrid DelkerDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Adrien HolzgreveDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Johannes TomsDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Franz Joseph GildehausDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Christoph J AuernhammerENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumours of the GastroEnteroPancreatic System (GEPNET-KUM), LMU University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0001-8087-3722
Christine SpitzwegENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumours of the GastroEnteroPancreatic System (GEPNET-KUM), LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Mathias J ZacherlDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Harun IlhanDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Johannes RübenthalerDepartment of Radiology, LMU University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0003-0832-5662
Leonie BeyerDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Lena M UnterrainerDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesPeptide Receptor Radionuclide Therapy (PRRT) is approved for patients with inoperable, progressive and/or metastatic well-differentiated NETs. Before the approval of Lutathera

methodsThe included patients with GEP NETs (

resultsThe occurrence of high-grade adverse events (CTCAE grade 3/4) after PRRT was moderate, with 1/10 (10%) grade 4 lymphocytopenia in the Lutathera

conclusionComparing the hematotoxicity in patients that were treated with locally manufactured

Indexed as

177Lu-HA-DOTATATEhematotoxicityLutathera®NETPRRT

Identifiers

PMID40361351
PMCPMC12070922

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.