Evidence map›Paper›PMID 40361348›Full record

ArticleCancers2025

Impact of Bowel Cleansing on Polyp and Adenoma Detection Rate: Post-Hoc Analysis of a Randomized Clinical Trial.

Marcello Maida, Roberto Vassallo, Alessandro Vitello, Angelo Zullo, Ludovica Venezia, Antonio Facciorusso

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marcello MaidaDepartment of Medicine and Surgery, University of Enna 'Kore', 94100 Enna, Italy.ORCID 0000-0002-4992-9289
Roberto VassalloGastroenterology Unit, Buccheri la Ferla Hospital, 90123 Palermo, Italy.
Alessandro VitelloDepartment of Medicine and Surgery, University of Enna 'Kore', 94100 Enna, Italy.ORCID 0000-0001-9099-9468
Angelo ZulloGastroenterology Unit, Nuovo Regina Margherita Hospital, 00153 Roma, Italy.
Ludovica VeneziaGastroenterology Unit, AOU Maggiore della Carità, 28100 Novara, Italy.
Antonio FacciorussoDepartment of Experimental Medicine, Università del Salento, 73100 Lecce, Italy.ORCID 0000-0002-2107-2156

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the impact of bowel cleansing quality on polyp detection rate (PDR) and adenoma detection rate (ADR) and explore predictors of lesion detection rate in patients undergoing colonoscopy.

methodsThis is a post-hoc analysis of a multicenter randomized controlled trial (RCT) comparing 1L polyethylene glycol plus ascorbate (1L PEG+ASC) vs. 4L PEG as bowel preparation for colonoscopy.

resultsPDR was significantly higher (35.6% vs. 18.5%,

conclusionsThis post-hoc analysis of a RCT showed that excellent cleansing (BBPS = 9) over high-quality cleansing (BBPS = 7-8) does not significantly improve PDR or ADR. Neither cleansing success nor preparation types were independently associated with ADR. Compliance with bowel preparation, timing of colonoscopy and withdrawal time are key elements for adequate ADR with potential implications for reducing interval colorectal cancer.

Indexed as

adenoma detection ratebowel preparationcleansingcolonoscopycolorectal cancerpolyethylene glycol

Identifiers

PMID40361348
PMCPMC12071129

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.