Evidence map›Paper›PMID 40361270›Full record

ArticleThe Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association2025

Identifying risk factors for adverse lung health outcomes among rural Appalachian women.

Jessica R Thompson, Courtney J Walker, John C Flunker, W Jay Christian, Wayne T Sanderson, Nancy E Schoenberg, Steven R Browning

Abstract read
In one paragraph

Article in The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Identifying risk factors for adverse lung health outcomes among rural Appalachian women.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jessica R ThompsonCommunity Impact Office, Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0002-6954-2663
Courtney J WalkerDepartment of Behavioral Sciences, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0003-3274-7304
John C FlunkerDepartment of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, Washington, USA.
W Jay ChristianDepartment of Epidemiology, College of Public Health, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0001-6904-3971
Wayne T SandersonDepartment of Epidemiology, College of Public Health, University of Kentucky, Lexington, Kentucky, USA.
Nancy E SchoenbergDepartment of Behavioral Sciences, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Steven R BrowningDepartment of Epidemiology, College of Public Health, University of Kentucky, Lexington, Kentucky, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDespite high rates of lung disease and lung cancer among women, few studies have focused on adverse lung health risk factors among rural Appalachian women. We aim to describe the prevalence of demographic, behavioral, and economic characteristics among a cohort of rural Appalachian women and ascertain the association between these risk factors and lung function.

methodsThrough a cross-sectional study in two rural Appalachian Kentucky counties (2015-2017), we collected demographics, health history/behaviors, and lung function via pulmonary function tests. Restricting to female participants with interpretable pulmonary function tests (N = 456), we estimated prevalence ratios of the association between individual-level characteristics and lung function using log binomial regression.

findingsReduced lung function was high among this sample, including 20.8% with restrictive function and 18.4% with obstructive function. After adjustment, those age 65+ had 7× the prevalence of obstructive function compared to those <45 years, and current smokers had 6× the prevalence of never-smokers. Conversely, those age 45-64 had over 5× the prevalence of restrictive function compared to those <45 years, and participants with an obese-classified BMI or 2+ co-morbidities had nearly 4× the prevalence of restrictive function compared to those with normal BMI or without a comorbid condition, respectively.

conclusionsThis study highlights the high levels of reduced lung function among rural Appalachian women, including varying risk factors between those with restrictive and obstructive function. The high prevalence of restrictive function among middle-aged women with high BMI, poor cardiovascular health, and multiple comorbidities suggests the need for culturally tailored health behavior interventions.

Indexed as

Lung DiseasesRural PopulationAdultAgedAppalachian RegionCross-Sectional StudiesFemaleHumansKentuckyMiddle AgedPrevalenceRespiratory Function TestsRisk FactorsAppalachian regionbinomial regressionlung functionsocial determinants of healthwomen's health

Identifiers

PMID40361270
PMCPMC12075779

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.