Evidence map›Paper›PMID 40361267›Full record

ArticleJournal of neuroimaging : official journal of the American Society of Neuroimaging

T

Madeleine Marshall, Kingkarn Aphiwatthanasumet, Olivier Mougin, Christine Stadelmann, Paul S Morgan, Rob A Dineen, Penny Gowland, Nikos Evangelou, Margareta A Clarke

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroimaging : official journal of the American Society of Neuroimaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Madeleine MarshallMental Health and Clinical Neurosciences Academic Unit, School of Medicine, University of Nottingham, Nottingham, UK.
Kingkarn AphiwatthanasumetSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
Olivier MouginSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
Christine StadelmannDepartment of Neuropathology, University Medical Centre Göttingen, Göttingen, Germany.
Paul S MorganMental Health and Clinical Neurosciences Academic Unit, School of Medicine, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0002-5870-1446
Rob A DineenMental Health and Clinical Neurosciences Academic Unit, School of Medicine, University of Nottingham, Nottingham, UK.
Penny GowlandSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
Nikos EvangelouMental Health and Clinical Neurosciences Academic Unit, School of Medicine, University of Nottingham, Nottingham, UK.
Margareta A ClarkeMental Health and Clinical Neurosciences Academic Unit, School of Medicine, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0001-5531-796X

Funding

Naresuan University, ThailandUniversity of Nottingham, UK
6 · The paper itself

Abstract

background and purposeChronic active multiple sclerosis (MS) lesions represent a particularly destructive subset of lesions on pathology. However, their imaging correlates, including paramagnetic rim lesions (PRLs) detected on susceptibility-weighted imaging, lack sensitivity and are difficult to implement in clinical practice. This exploratory, longitudinal study investigates the prevalence and temporal dynamics of a novel imaging marker, T

methodsFour untreated people with MS underwent 7-Tesla MRI scanning six times over a period of 36 weeks. New and pre-existing lesions were analyzed for the presence and temporal evolution of T

resultsOf the 159 baseline lesions, 22 (14%) had T

conclusionsT

Indexed as

BrainMagnetic Resonance ImagingMultiple SclerosisAdultChronic DiseaseDisease ProgressionFemaleHumansLongitudinal StudiesMaleMiddle Aged7Tchronic active lesionMP2RAGEmultiple sclerosisparamagnetic rim lesionquantitative susceptibility mappingT1‐dark rim

Identifiers

PMID40361267
PMCPMC12075677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.