Evidence map›Paper›PMID 40361258›Full record

ArticleWorldviews on evidence-based nursing2025

The Relationship Between Depression, Burnout, and Suicide Among Healthcare Professionals: A Scoping Review.

Nam Nguyen, Elizabeth Spooner, Pamela O'Balle, Hannan Ashraf, Karen Heskett, Sidney Zisook, Judy E Davidson

Abstract readScoping Review
In one paragraph

Article in Worldviews on evidence-based nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nam NguyenDepartment of Psychiatry, University of California, San Diego, USA.ORCID https://orcid.org/0009-0006-0459-6683
Elizabeth SpoonerDepartment of Psychiatry, University of California, San Diego, USA.ORCID https://orcid.org/0009-0006-1790-0680
Pamela O'BalleDepartment of Psychiatry, University of California, San Diego, USA.ORCID https://orcid.org/0009-0003-1379-8760
Hannan AshrafDepartment of Psychiatry, University of California, San Diego, USA.ORCID https://orcid.org/0009-0004-2623-7898
Karen HeskettSchool of Medicine, University of California, San Diego, USA.ORCID https://orcid.org/0000-0003-4501-6172
Sidney ZisookSan Diego School of Medicine, Department of Psychiatry, Distinguished Professor, University of California, San Diego, USA.ORCID https://orcid.org/0000-0003-3341-9185
Judy E DavidsonDepartment of Psychiatry, University of California, San Diego, USA.ORCID https://orcid.org/0000-0003-1459-181X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBurnout and mental health concerns are prevalent among healthcare workers. Female physicians, nurses, and healthcare staff are at a higher risk of suicide than the general population. Burnout and depression have been known to coexist with suicidal ideation and behaviors.

aimsTo identify what is known about the relationship between burnout and depression in the context of suicide among healthcare workers.

methodsRegistered scoping review of English language articles indexed to CINAHL, PubMed, and PsychInfo databases with date of publication prior to March 5, 2024.

resultsThe review yielded nine eligible studies, all employing observational or descriptive methodologies. Depression was found to be a predictor of suicidal ideation. While burnout was associated with depressive symptoms and found to coexist with suicidal ideation, it was not predictive of ideation. Emotional exhaustion and depersonalization were key components of burnout linked to depression. No studies were found exploring survivorship factors in healthcare professionals. Suggested prevention strategies that need to be tested include mindfulness and cognitive-behavioral skills training, improved workplace conditions, addressing loneliness, and fostering resilience. LINKING EVIDENCE TO ACTION: Interventional studies are needed to test strategies addressing burnout, depression, suicidal behaviors, and survivorship of suicide attempts. Depression should be considered and evaluated when healthcare workers exhibit symptoms of burnout. Moreover, the Socio-economic Model of Suicide Prevention (i.e., SESM) can be used to categorize suicide prevention measures in healthcare. Burnout and depression interact to influence mental health outcomes among healthcare professionals, with depression playing a more significant role in predicting suicidal ideation. Despite the demonstrated relationships, critical gaps in knowledge exist in understanding survivorship and in the development and testing of effective interventions. Future interventional multisite research is needed using validated tools to identify best practices in suicide prevention for healthcare professionals.

Indexed as

Burnout, ProfessionalDepressionHealth PersonnelSuicideHumansburnoutcompassion fatiguedepressionemotional exhaustionhealthcare workersmental healthoccupational stresssuicidal behaviorssuicide preventionworkplace well‐being

Identifiers

PMID40361258
PMCPMC12075674

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.