Evidence map›Paper›PMID 40361224›Full record

ReviewJournal of anesthesia, analgesia and critical care2025

Enhancing Safety in Regional Anesthesia: Guidelines from the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI).

Vito Torrano, Salvatore Anastasi, Eleonora Balzani, Enrico Barbara, Astrid Ursula Behr, Mario Bosco, Claudio Buttarelli, Silvia Bruletti, Dario Bugada, Chiara Cadeddu and 21 more

Abstract readReview
In one paragraph

Review in Journal of anesthesia, analgesia and critical care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. ARDS management in trauma patients.Intensive care medicine · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Frailty in anesthesia.Current opinion in anaesthesiology · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Vito TorranoDepartment of Anesthesia, Critical Care and Pain Medicine, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Salvatore AnastasiDepartment of Anesthesiology and Intensive Care, Nesima, Catania, Italy.
Eleonora BalzaniDepartment of Surgical Sciences, University of Turin, Turin, Italy.
Enrico BarbaraDepartment of Anesthesiology and Intensive Care, Humanitas Mater Domini, Castellanza, Varese, Italy.
Astrid Ursula BehrDepartment of Anesthesiology and Intensive Care, ULSS 6 Euganea, Padua, Italy.
Mario BoscoDepartment of Anesthesiology and Intensive Care, ASL Roma 1, Rome, Italy.
Claudio ButtarelliInstitute of Anesthesia, Treviso Hospital, Treviso, Italy.
Silvia BrulettiCardinal Gusmini Foundation-ONLUS, Vertova, Bergamo, Italy.
Dario BugadaDepartment of Emergency and Critical Care, ASST Papa Giovanni XXIII, Bergamo, Italy.
Chiara CadedduErasmus School of Health Policy and Management, Erasmus University Rotterdam, Rotterdam, Netherlands.
Gianluca CappelleriDepartment of Anesthesia, Intensive Care and Pain Medicine, Monza Polyclinic, Monza, Monza-Brianza, Italy.
Luigi CardiaDepartment of Pain Medicine, University Hospital "Gaetano Martino", Messina, Italy.
Salvatore CasaranoAnesthesiology Department, Pia Fondazione Tricase, Lecce, Italy.
Andrea CortegianiDepartment of Anesthesia Intensive Care and Emergency, Policlinico Paolo Giaccone, Palermo, Italy.
Floriana D'AmbrosioSection of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Miryam Del VicarioDepartment of Anesthesiology and Intensive Care Medicine, "Agostino Gemelli" University Polyclinic Foundation IRCCS - Catholic University of The Sacred Heart, Rome, Italy.
Andrea FanelliDepartment of Anesthesia, Intensive Care and Pain Medicine, Monza Polyclinic, Monza, Monza-Brianza, Italy.
Pierfrancesco FuscoDepartment of Anesthesia, Intensive Care and Pain Medicine, SS. Filippo E Nicola Hospital, Avezzano, L'Aquila, Italy.
Giuseppe GazzerroDepartment of Anesthesiology, Intensive Care and Pain Medicine, AORN Dei COLLI Monaldi-CTO, Naples, Italy.
Daniela GhisiDepartment of Anesthesia, Intensive Care and Pain Medicine, Monza Polyclinic, Monza, Monza-Brianza, Italy.
Antonino GiarratanoDepartment of Anesthesia Intensive Care and Emergency, Policlinico Paolo Giaccone, Palermo, Italy.
Fabio GoriDepartment of Anesthesiology and Intensive Care 1, Perugia Hospital, Perugia, Italy.
Massimiliano GrecoDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Paolo Angelo GrossiAnesthesia, Critical Care and Pain Medicine Consultant, ASST Gaetano Pini-CTO, Milan, Italy.
Alberto ManasseroUnit of Anesthesia, Casa Di Cura Città Di Bra, Cuneo, Italy.
Gianluca RussoAnesthesia and Intensive Care, ASST Lodi, Lodi, Italy.
Salvatore SardoDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Cosimo SavoiaSection of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Marco TescioneDepartment of Anesthesiology and Critical Care, Bianchi-Melacrino-Morelli Health Institute of Reggio Calabria, Reggio Calabria, Italy.
Giulia TintiSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy. giuliatinti@yahoo.it.
Alessandro De CassaiDepartment of Medicine (DIMED), University of Padua, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRegional anesthesia techniques have become integral to modern perioperative care, offering enhanced pain management and recovery outcomes. However, their application in patients with specific conditions, such as anticoagulation therapy or preexisting comorbidities, raises concerns regarding safety and efficacy. Current guidelines addressing these issues are fragmented, necessitating comprehensive, evidence-based recommendations.

methodsA multidisciplinary panel of experts in anesthesiology and pain management was convened under the auspices of the Italian Society of Anesthesia, Analgesia, Resuscitation, and Intensive Care (SIAARTI). The guidelines presented herein were developed according to the GRADE system (Grading of Recommendations of Assessment Development and Evaluations), in compliance with the methodological manual for the production of clinical practice guidelines published by the National Center for Clinical Excellence, Quality, and Safety of Care, Italian National Institute of Health.

resultsThe guidelines encompass recommendations on neuraxial blocks in anticoagulated patients, the dual guidance use in peripheral nerve blocks, the role of sterile field preparation, and post-procedural monitoring. Evidence from meta-analyses and large-scale observational studies supported most recommendations, though limitations in study heterogeneity were noted.

conclusionsThese guidelines provide a structured framework for clinicians to enhance patient safety and procedural efficacy in regional anesthesia. Further research is encouraged to address identified gaps, particularly regarding specific patient subgroups and novel regional anesthesia techniques.

Indexed as

AnticoagulationNeuraxial blocksPatient safetyRegional anesthesiaUltrasound guidance

Identifiers

PMID40361224
PMCPMC12076962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.