ArticleBiomedical engineering online2025
Preparation and characterization of human decellularized ovarian scaffold based on supercritical carbon dioxide protocol.
Article in Biomedical engineering online, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Decellularization of porcine dermis via supercritical CORegenerative biomaterials · 2026Article
- Fabrication of testicular decellularized scaffolds using a hybrid SDS-supercritical CO₂ method: process optimization, extracellular matrix preservation, and biocompatibility evaluation.Biomedical engineering online · 2025Article
- Strategies in Tissue Regenerative Engineering for the Treatment of Human Infertility.Stem cell reviews and reports · 2025Review
- Fertility in early breast cancer patients: integrating reproductive planning into oncology care.Frontiers in endocrinology · 2025Review
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Authors and funding
5 authors.
Funding
Abstract
backgroundPrimary ovarian insufficiency affecting 1-3% of women under 40, causes premature menopause and estrogen deficiency. With increasing life expectancy, a large percentage of women also face estrogen-related symptoms. A bioengineered ovary is one of the strategies to replace or enhance ovarian tissue function. A key advancement in bioengineering is the development of ovarian decellularized extracellular matrix scaffolds that mimic natural ovarian niche. Recent studies indicate that supercritical carbon dioxide (scCo
methodsWe evaluated two distinct pressure conditions (200 and 300 bar), while maintaining identical thermal (40 °C) and temporal (1.5 h) parameters, during the scCO
resultsApplication of 1% SDS, while utilizing the scCO
conclusionsWe propose an optimal protocol utilizing 1% SDS as a pretreatment, followed by the scCO
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