ArticleBMC surgery2025
Early cranioplasty versus traditional cranioplasty enhances surgical outcomes in patients with malignant cerebral infarction after decompressive craniectomy.
Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Timing of cranioplasty after decompressive craniectomy and neurological recovery: A systematic review and meta-analysis.Neurosurgical review · 2026Pooled it
- Early Versus Delayed Cranioplasty After Decompressive Craniectomy: A Systematic Review and Meta-Analysis.Brain and behavior · 2026Pooled it
- Ultrasound-guided needle technique as a relaxation strategy for early cranioplasty: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Timing and Outcomes of Cranioplasty After Decompressive Craniectomy: A Systematic Review of Neurological Recovery, Complications, and Predictive Factors.Journal of clinical medicine · 2026Review
- Precision dissection strategy for myocutaneous flap in frontotemporal cranioplasty based on tissue biophysical properties.Frontiers in surgery · 2026Article
- The timing of cranioplasty and the risk of postoperative complications: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Cerebral Perfusion and Blood-Brain Barrier Changes After Cranioplasty: A Diffusion-Prepared Arterial Spin Labeling Study.Journal of neuroimaging : official journal of the American Society of NeuroimagingArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA growing cohort of malignant cerebral infarction (MCI) patients after decompressive craniectomy (DC) required cranioplasty (CP). However, few studies have reported the effect of CP on functional improvements in post-DC MCI patients. The aim of this study was to determine whether early CP for post-DC MCI patients enhances surgical outcomes and alters overall complication rate.
methods86 post-DC MCI patients after CP were divided into the early CP cohort and the traditional CP cohort according to the time span from DC to CP. Complications, NIHSS, mBI, mRS, and CRS-r were assessed, and early CP and traditional CP were defined as occurring less than or more than 3 months after DC.
resultsComplications were observed in 9 patients (24.32%) in the early CP cohort and 14 patients (28.57%) in the traditional CP cohort (p > 0.05). NIHSS, mRS, mBI, and CRS-r between pre-operation and post-operation did significantly differ (p < 0.05). Between the two cohorts, operative time, intraoperative blood loss, post-operative parameters (NIHSS, mBI and mRS), ∆NIHSS, and ∆mBI did significantly differ (p < 0.05), while post-operative CRS-r did not significantly differ (p > 0.05). There was a linear relationship between ∆NIHSS and the time span from DC to CP (r = 0.505, p < 0.0001), and there was a linear relationship between ∆BI and the time span from DC to CP (r = -0.568, p < 0.0001).
conclusionsOur study demonstrated that, first, CP has a favorable effect on improving neurological function, ability to perform daily living, and consciousness in post-DC MCI patients; second, early CP does not alter the overall complication rate and is as safe as traditional CP; third, compared to traditional CP, early CP reduces operative time and intraoperative blood loss, promotes improvements in neurological function and ability to perform daily living, and enhances these improvements.
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