SynthesisBMC urology2025
The impact of warm ischemia time on short-term renal function after partial nephrectomy: a systematic review and meta-analysis.
Synthesis in BMC urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Safety and feasibility of robotic telesurgery in urological procedures: a systematic review and meta-analysis of clinical data.Journal of robotic surgery · 2026Pooled it
- Robot-assisted versus open partial nephrectomy in renal tumor patients with chronic kidney disease: a meta-analysis of renal functional and perioperative outcomes.Journal of robotic surgery · 2025Pooled it
- The Role of Near-Infrared Fluorescence with Indocyanine Green in Robot-Assisted Partial Nephrectomy: Results from an Updated Systematic Review and Meta-Analyses of Controlled Studies.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Modified internal traction technique for improved exposure in retroperitoneal robot-assisted partial nephrectomy for dorsal hilar tumors: a preliminary single-center experience.Journal of robotic surgery · 2026Article
- Renal functional outcomes after minimally invasive partial nephrectomy, single-surgeon experience.BJUI compass · 2026Article
- Impact of robotic access and dedicated kidney surgery teams on nephron-sparing surgery for T1 renal masses: evidence from a Spanish multicenter registry.Journal of robotic surgery · 2026Article
- Intraoperative Doppler Verification of Arterial Occlusion in Minimally Invasive Renal Resection.Urologia internationalis · 2026Article
- Surgical Determinants of Outcomes in Partial Nephrectomy: a Contemporary Review.Current urology reports · 2026Review
- Selective Artery Clamping Superior to Main Artery Clamping in Preserving Ipsilateral Renal Function after Minimally Invasive Partial Nephrectomy under Prolonged Warm Ischemia.Annals of surgical oncology · 2026Article
- Effect of perioperative dexmedetomidine on acute kidney injury after partial nephrectomy. Comment on Br J Anaesth 2025; 135: 1212-22.British journal of anaesthesia · 2026Article
- Association of PADUA and RENAL scores with early perioperative outcomes in large renal tumors managed with robot-assisted partial nephrectomy.Frontiers in surgery · 2026Article
- Comparison of robotic and laparoscopic partial nephrectomy in the management of solitary kidney tumors: a retrospective single-center study (2012-2025).BMC surgery · 2025Article
- [Remimazolam stabilizes hemodynamics during anesthesia induction but fails to reduce renal injury risk following laparoscopic partial nephrectomy: a propensity score-matched retrospective cohort study].Nan fang yi ke da xue xue bao = Journal of Southern Medical UniversityArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeThis study aimed to assess the impact of warm ischemia time on short-term renal function in individuals undergoing partial nephrectomy.
methodsWe conducted a comprehensive search for primary research articles from 1990 to October 15, 2024 across several databases, including MEDLINE, Embase and the Cochrane Library. A random effects model was applied to determine multivariable adjusted odds ratios (ORs) and their corresponding 95% confidence intervals (CIs). Country and study design were utilised as outcome indicators in the regression model.
resultsTen studies including 4,993 patients who underwent partial nephrectomy met the inclusion criteria. The threshold of potentially harmful ischemia time for renal artery occlusion ranges between 10 and 45 min. Our results revealed that long warm ischemia time was associated with decreased postoperative eGFR and poor short-term renal function (OR = 1.08; 95% CI = 1.02-1.15; P = 0.006) after partial nephrectomy. Sensitivity and meta-regression analyses demonstrated the robustness of the study's findings.
conclusionsExtended periods of warm ischemia, specifically exceeding 25-30 min, can inflict damage on kidneys undergoing surgical treatment. Minimising the duration of warm ischemia while simultaneously prioritising surgical safety and achieving clear margins is imperative. Moreover, ischemia time remains a modifiable risk factor and must be reduced to maintain overall short-term renal function. Relevant prospective and randomised controlled trials must be conducted to validate these findings. PROSPERO REGISTRATION NUMBER: CRD42024560051.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.