Evidence map›Paper›PMID 40360979›Full record

ArticleBMC gastroenterology2025

Red cell distribution width as a potential new biomarker to predict the clinical severity of acute diverticulitis.

Melek Yalcin Koc, Mehmet Aykut Yildirim, Suleyman Sakir Tavli, Abdullah Gurhan Duyan

Abstract read
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Jejunal diverticular disease: A gastrointestinal bleeding enigma.World journal of gastrointestinal pathophysiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Melek Yalcin KocDepartment of General Surgery, SBU Beyhekim Training and Research Hospital, Akademi Devlethane Sokak No:8/B, Selçuklu, Konya, 42060, Turkey. melekyalcinmd37@gmail.com.ORCID http://orcid.org/0009-0008-7725-1437
Mehmet Aykut YildirimDepartment of General Surgery, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.ORCID http://orcid.org/0000-0001-9580-6004
Suleyman Sakir TavliDepartment of General Surgery, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.ORCID http://orcid.org/0009-0009-8018-9520
Abdullah Gurhan DuyanDepartment of General Surgery, Konya City Hospital, Konya, Turkey.ORCID http://orcid.org/0000-0003-2571-976X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationships between red cell distribution width (RDW), other inflammation-related markers and clinical features with the clinical and radiological severity of diverticulitis.

methodsThis retrospective cohort study included 250 patients diagnosed with acute diverticulitis. Radiological diverticulitis severity was determined by the Hinchey classification. Clinical diverticulitis severity was determined based on the treatment applied (invasive versus conservative/medical treatment).

resultsHigh platelet count (p = 0.001) and high CRP (p < 0.001) were independently associated with the Hinchey Class II-IV. Need for invasive treatment was independently associated with presence of Hinchey stage II-IV (p < 0.001) and high (> 13.75) RDW (p < 0.001). With a cut-off value of > 13.75, RDW was able to predict patients requiring invasive treatment [Sensitivity = 75.86%, Specificity = 63.87%, AUC (95% CI) = 0.657 (0.580-0.734), p < 0.001]. CONCLUSIOSN: RDW, which is an inexpensive and readily-available parameter, may be a supportive measure in the prediction of the clinical severity of diverticulitis. Together with other clinical and laboratory data, RDW could help identify patients with worse prognosis, facilitating appropriate decisions and precautions in their management.

Indexed as

DiverticulitisDiverticulitis, ColonicErythrocyte IndicesAcute DiseaseAdultAgedAged, 80 and overBiomarkersC-Reactive ProteinFemaleHumansMaleMiddle AgedPlatelet CountPredictive Value of TestsRetrospective StudiesBiomarkersC-Reactive ProteinBiomarkersC-reactive proteinDiverticulitisPrognosisRed cell distribution width

Identifiers

PMID40360979
PMCPMC12070636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.