Evidence map›Paper›PMID 40360977›Full record

Observational studyBMC infectious diseases2025

Risk stratification and conservative management of women aged 25-40 years with cervical intraepithelial neoplasia grade 2(CIN2).

Huanhua Wang, Ping Jin

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Huanhua Wang *Department of Gynecology, Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, No. 3012, Fuqiang Road, Futian District, Shenzhen, Guangdong Province, 518017, China. wanghuanhua@126.com.ORCID http://orcid.org/0000-0001-8878-8012
Ping Jin *Department of Gynecology, Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, No. 3012, Fuqiang Road, Futian District, Shenzhen, Guangdong Province, 518017, China.ORCID http://orcid.org/0000-0001-9668-4969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical intraepithelial neoplasia grade 2 (CIN2) can progress to CIN3 or worse (CIN3

methodsWe conducted a retrospective observational study of 307 women aged ≤ 40 years, diagnosed with CIN2 via colposcopy-guided punch biopsy where the squamocolumnar junction was visible, and who underwent LEEP within three months. We compared the diagnoses from punch biopsies with the histology of the LEEP specimens and developed a stratified management algorithm based on identified risk factors.

resultsThe risk of CIN3

conclusionPatients aged 25-40 years with CIN2 diagnosed in punch biopsy exhibited a substantial risk of CIN3

Indexed as

Conservative TreatmentPapillomavirus InfectionsUterine Cervical DysplasiaUterine Cervical NeoplasmsAdultBiopsyColposcopyElectrosurgeryFemaleHumansRetrospective StudiesRisk AssessmentRisk FactorsCervical cancer preventionCervical intraepithelial neoplasia 2ConizationConservative treatmentCytologyHPV genotype

Identifiers

PMID40360977
PMCPMC12076850

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.