Evidence map›Paper›PMID 40360732›Full record

ReviewNature reviews. Urology2025

XYGO: proposing a new holistic measure of gender identity and sexual orientation.

Alexi Di Cristofaro, Tommaso B Jannini, Elena Colonnello, Erika Limoncin, Daniele Mollaioli, Giacomo Ciocca, Andrea Sansone, Emmanuele A Jannini

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexi Di Cristofaro *Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.ORCID 0009-0009-1944-4107
Tommaso B Jannini *School of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0003-2936-4150
Elena ColonnelloDepartment of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0002-0081-7163
Erika LimoncinSection of Sexual Psychopathology, Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Rome, Italy.
Daniele MollaioliSection of Psychometry, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Giacomo CioccaSection of Sexual Psychopathology, Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-4256-1776
Andrea SansoneDepartment of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Emmanuele A JanniniDepartment of Systems Medicine, University of Rome Tor Vergata, Rome, Italy. eajannini@gmail.com.ORCID 0000-0002-5874-039X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gender identity (GI) and sexual orientation (SO) are key aspects of an individual's sexual identity, which is a major driver of human sexuality. Although definitions for GI and SO have been long established and represented in clinical and theoretical research, often without acknowledgement of their relationship to one another, the ideal means by which they should be measured is unclear. Various tools for measurement have been proposed, each presenting different methodological approaches along with their respective flaws and issues. By providing a comprehensive overview of the major instruments for measuring GI and SO, the XYGO tool aims to integrate their strengths by developing a new, cohesive and inclusive perspective on sexual identity, taking into consideration both dimensions of this unique characteristic of human sexuality. This holistic perspective integrates these components into a single construct capable of providing a more immediate and tailored interpretation to facilitate everyday clinical practice and potentially improve research in sexual medicine and psychosexology.

Indexed as

Gender IdentitySexual BehaviorSexualityFemaleHumansMale

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.