Evidence map›Paper›PMID 40360731›Full record

ArticleNPJ digital medicine2025

Integrating personalized shape prediction, biomechanical modeling, and wearables for bone stress prediction in runners.

Liangliang Xiang, Yaodong Gu, Kaili Deng, Zixiang Gao, Vickie Shim, Alan Wang, Justin Fernandez

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Interpretable prediction of knee joint loading during tennis serves based on GNN-GRU model and layer-wise relevance propagation.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liangliang XiangFaculty of Sports Science, Ningbo University, Ningbo, China.
Yaodong GuFaculty of Sports Science, Ningbo University, Ningbo, China. guyaodong@nbu.edu.cn.
Kaili DengSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Zixiang GaoFaculty of Sports Science, Ningbo University, Ningbo, China.
Vickie ShimAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Alan WangAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Justin FernandezAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.

Funding

Key Research and Development Program of Zhejiang Province 2021C03130Science Fund for Distinguished Young Scholars of Zhejiang Province LR22A020002
6 · The paper itself

Abstract

Running biomechanics studies the mechanical forces experienced during running to improve performance and prevent injuries. This study presents the development of a digital twin for predicting bone stress in runners. The digital twin leverages a domain adaptation-based Long Short-Term Memory (LSTM) algorithm, informed by wearable sensor data, to dynamically simulate the structural behavior of foot bones under running conditions. Data from fifty participants, categorized as rearfoot and non-rearfoot strikers, were used to create personalized 3D foot models and finite element simulations. Two nine-axis inertial sensors captured three-axis acceleration data during running. The LSTM neural network with domain adaptation proved optimal for predicting bone stress in key foot bones-specifically the metatarsals, calcaneus, and talus-during the mid-stance and push-off phases (RMSE < 8.35 MPa). This non-invasive, cost-effective approach represents a significant advancement for precision health, contributing to the understanding and prevention of running-related fracture injuries.

Identifiers

PMID40360731
PMCPMC12075602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.