Evidence map›Paper›PMID 40360704›Full record

Observational studyScientific reports2025

A cohort study evaluating myocardial work and right ventricle strain in sepsis in critical care.

Thomas Sanderson, Theophilus Samuels

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thomas SandersonSurrey and Sussex Healthcare NHS Trust, East Surrey Hospital, Redhill, Surrey, RH15RH, UK.
Theophilus SamuelsSurrey and Sussex Healthcare NHS Trust, East Surrey Hospital, Redhill, Surrey, RH15RH, UK. theophilus.samuels1@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The understanding of sepsis-related changes in myocardial function is evolving. This single-centre prospective observational cohort pilot study evaluated myoCardial work and Right ventricle Strain In Sepsis (CRiSIS) with 30-day mortality in critical care patients. Measurements were recorded for 32 patients on days 1 and 3 of admission: 22 (69%) survivors and 10 (31%) non-survivors at 30 days. Survivors demonstrated a higher global work efficiency (GWE; 94%, IQR 91-96%) compared to non-survivors (88.5%, IQR 85-92%; p = 0.02, BF

Indexed as

Heart VentriclesSepsisAgedBayes TheoremCritical CareCritical IllnessFemaleHumansMaleMiddle AgedPilot ProjectsProspective StudiesCardiacMortalityMyocardialSepsisStrainWork

Identifiers

PMID40360704
PMCPMC12075690

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.