Evidence map›Paper›PMID 40360633›Full record

ArticleScientific reports2025

Association between Neutrophil Percentage-to-Albumin ratio and anemia risk: a population-based study.

Songting Gao, Fuqin Yu, Yueyuan Han

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Songting GaoGuali Branch of the First People's Hospital of Xiaoshan District, Hangzhou, 311200, Zhejiang, People's Republic of China.
Fuqin YuGuali Branch of the First People's Hospital of Xiaoshan District, Hangzhou, 311200, Zhejiang, People's Republic of China.
Yueyuan HanThe First People's Hospital of Xiaoshan District, Hangzhou, 311200, Zhejiang, People's Republic of China. yyhan2023@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anemia remains a significant global health challenge, driven by complex inflammatory mechanisms. This study investigated the association between neutrophil percentage-to-albumin ratio (NPAR) and anemia risk, utilizing data from 24,938 participants in the National Health and Nutrition Examination Survey (2005-2018). Multivariable logistic regression analysis revealed a significant association between NPAR and anemia risk (OR = 1.16; 95% CI 1.13-1.18, p < 0.0001). Two-piecewise regression analysis identified a nonlinear relationship with a threshold at NPAR 11.96: below this threshold, an inverse association was observed (OR = 0.88; 95% CI 0.79-0.98, p = 0.0249), while above it, a positive association was evident (OR = 1.21; 95% CI 1.18-1.25, p < 0.0001). Subgroup analyses demonstrated stronger associations in males, non-Hispanic Whites, diabetic patients, and individuals who were married or living with a partner. These findings highlight the potential of NPAR as a novel biomarker for assessing anemia risk in clinical practice.

Indexed as

AnemiaNeutrophilsSerum AlbuminAdultAgedBiomarkersFemaleHumansLeukocyte CountMaleMiddle AgedNutrition SurveysRisk FactorsBiomarkersSerum AlbuminAnemiaInflammation markerNHANESNPAR

Identifiers

PMID40360633
PMCPMC12075635

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.