ArticleScientific reports2025
Development of ZnO-NPs reinforced chitosan nanofiber mats with improved antibacterial and biocompatibility properties.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Polymer-stabilized amorphous CuO-ZnO hybrid nanocomplex as a promising candidate for antimicrobial therapy and controlled drug delivery with molecular docking insights.Scientific reports · 2026Article
- Marine macroalgae-mediated ultrasonic-assisted green synthesis of CuO nanoparticles embedded in starch/PVA electrospun nanoscaffolds for in vitro α-amylase and α-glucosidase inhibitory activity.Scientific reports · 2026Article
- Biofabrication ofPharmaceutics · 2026Article
- Modeling and experimental analyses for Chitosan/Zinc oxide nanocomposite.Scientific reports · 2026Article
- Lipid membrane-camouflaged biomimetic nanoparticle for MicroRNA based therapeutic delivery to intestinal epithelial cells.Scientific reports · 2025Article
- A Review of Chitosan-Based Electrospun Nanofibers for Food Packaging: From Fabrication to Function and Modeling Insights.Nanomaterials (Basel, Switzerland) · 2025Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper studied the possibility of fabricating a nano-composite based on chitosan incorporated with ZnO-NPs as a promising textile for wound dressing purposes. The nanofiber mat was obtained from dispersions of ZnO-NPs in chitosan-based solution blended with PVA (Cs/PVA/ZnO-NPs scaffold). The extracted chitosan was characterized using FTIR, FE-SEM, XRD, and TGA analysis. The electrospinning optimization process was successfully done for Cs and PVA mixture and a good combination of polymers, solvent, and the ratios developed through an optimization process (10wt.% PVA and 1wt.% CS in AcAcetic 80%). The nanofibers had an average diameter below 200 nm, while the incorporation of ZnO-NPs decreased their average diameter below 150 nm. FTIR, FE-SEM, XRD analysis were used to evaluate the scaffold structure. The FE-SEM analysis proved the smooth and bead-free morphology of the fibers. Elemental analysis of the mat revealed a good distribution of ZnO-NPs along nanofibers. Cell culture studies with L929 mouse fibroblast cells revealed good viability of the cell on the Cs/PVA/ZnO-NPs scaffold. The nanoparticles improved capability of the mat for growth inhibition rate of bacterial colonies and also its wettability. The results also showed the nontoxicity of CS/PVA/ZnO-NPs composite and its considerable potential for future application in wound dressing.
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