Evidence map›Paper›PMID 40360615›Full record

ArticleScientific reports2025

Efficacy and safety outcomes of the Paul glaucoma implant compared to the Ahmed glaucoma valve.

Angi Lizbeth Mendoza-Moreira, Julia V Stingl, Anna Maria Voigt, Jasmin Rezapour, Achim Fiess, Felix Mathias Wagner, Alexander K Schuster, Esther M Hoffmann

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Two-year efficacy and safety outcomes of the Paul Glaucoma Implant compared to the Ahmed Glaucoma Valve.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  4. One-year outcomes of the PAUL glaucoma implant versus ahmed glaucoma valve for the treatment of glaucoma following cataract surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Angi Lizbeth Mendoza-MoreiraDepartment of Ophthalmology, University Medical Center Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany. amendoza@uni-mainz.de.ORCID http://orcid.org/0000-0001-8643-7593
Julia V StinglDepartment of Ophthalmology, University Medical Center Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.ORCID http://orcid.org/0009-0007-5075-7377
Anna Maria VoigtDepartment of Ophthalmology, University Medical Center Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
Jasmin RezapourDepartment of Ophthalmology, University Medical Center Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
Achim FiessDepartment of Ophthalmology, University Medical Center Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
Felix Mathias WagnerDepartment of Ophthalmology, University Medical Center Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
Alexander K SchusterDepartment of Ophthalmology, University Medical Center Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
Esther M HoffmannDepartment of Ophthalmology, University Medical Center Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany. ehoffman@uni-mainz.de.ORCID http://orcid.org/0000-0002-0949-4268

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compares the one-year outcomes of standalone Ahmed glaucoma valve (AGV) implantation and standalone Paul glaucoma implant (PGI) in adult patients with primary and secondary glaucoma. A retrospective, single-center, comparative study was conducted on adult patients who underwent standalone PGI and AGV at the University Medical Center Mainz. The primary outcome measures were the changes of IOP and the number of antiglaucoma eye medication at one year postoperatively. Secondary outcome measures included complete and qualified success rates, failure rates, visual acuity logMAR and the incidence of adverse events. A total of 24 adult patients were included in the AGV group and 28 in the PGI group. The median preoperative intraocular pressure decreased from 29.5mmHg (Interquartile range (IQR) 21-42) to 16.0mmHg (IQR 7-37) in the AGV group, and from 34.0 mmHg (IQR 13-56) to 16.0 (IQR 7-21) mmHg in the PGI group at the one-year follow-up. The median number of classes of intraocular pressure-lowering medications reduced from 3.5 to 0 in the AGV group, and from 3.0 to 0 in the PGI group. There were no statistically significant differences between the groups for any success criteria or failure. The AGV produced more encapsulation than the PGI, and the latter more tube exposures. Both the Ahmed Glaucoma Valve and the Paul Glaucoma Implant effectively reduce IOP and the number of antiglaucoma medications at one year with comparable safety profiles.

Indexed as

GlaucomaGlaucoma Drainage ImplantsIntraocular PressureAdultAgedFemaleHumansMaleMiddle AgedPatient SafetyRetrospective StudiesTreatment OutcomeVisual AcuityAhmed glaucoma valveDrainageGlaucomaPaul glaucoma implantTube

Identifiers

PMID40360615
PMCPMC12075782

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.