Evidence map›Paper›PMID 40360565›Full record

ArticleScientific reports2025

Recent updates of the MPEXS2.1-DNA Monte Carlo code for simulations of water radiolysis under ion irradiation.

Shogo Okada, Koichi Murakami, Tamon Kusumoto, Yoshiyuki Hirano, Katsuya Amako, Takashi Sasaki

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shogo OkadaHigh Energy Accelerator Research Organization (KEK), 1-1, Oho, Tsukuba, Ibaraki, 305-0801, Japan. shogo.okada@kek.jp.
Koichi MurakamiHigh Energy Accelerator Research Organization (KEK), 1-1, Oho, Tsukuba, Ibaraki, 305-0801, Japan.
Tamon KusumotoNational Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.
Yoshiyuki HiranoGraduate School of Medicine, Biomedical Imaging Sciences, Nagoya University, 1-1-20 Daiko-Minami, Higashi-ku, Nagoya City, Aichi Prefecture, Japan.
Katsuya AmakoHigh Energy Accelerator Research Organization (KEK), 1-1, Oho, Tsukuba, Ibaraki, 305-0801, Japan.
Takashi SasakiHigh Energy Accelerator Research Organization (KEK), 1-1, Oho, Tsukuba, Ibaraki, 305-0801, Japan.

Funding

JSPS KAKENHI Grant 21H04881JSPS KAKENHI Grant 21K12246
6 · The paper itself

Abstract

To improve radiotherapy, especially that with ion beams such as proton and carbon ion beams, the mechanisms of interactions induced by ionizing radiation must be understood. MPEXS2.1-DNA is a Monte Carlo simulation code developed for water radiolysis studies and DNA damage simulations that uses GPU devices for fast computation. However, the original chemistry model in MPEXS2.1-DNA did not include detailed chemical reactions for reactive oxygen species (ROS), e.g., O

Indexed as

DNAMonte Carlo MethodWaterComputer SimulationDNA DamageIonsRadiation, IonizingReactive Oxygen SpeciesDNAIonsReactive Oxygen SpeciesWaterGPGPUMonte Carlo simulationRadiation chemistryRadiation physicsWater radiolysis simulation

Identifiers

PMID40360565
PMCPMC12075733

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.