Evidence map›Paper›PMID 40360564›Full record

ArticleScientific reports2025

A novel approach for synthesizing silver nanoparticles with antibacterial and cytotoxic activities using the leaf extract of hydroponically grown Moringa oleifera.

Anush Aghajanyan, Marina Timotina, Tatevik Manutsyan, Ani Harutyunyan, Mikayel Ginovyan, Robin Schubert, Sofiya Aydinyan, Karen Trchounian, Lilit Gabrielyan, Liana Gabrielyan

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anush AghajanyanDepartment of Biochemistry, Microbiology and Biotechnology, Biology Faculty, Yerevan State University, Yerevan, 0025, Armenia. a.aghajanian@ysu.am.
Marina TimotinaDepartment of Medical Biochemistry and Biotechnology, Russian-Armenian University, Yerevan, 0051, Armenia.
Tatevik ManutsyanDepartment of Biochemistry, Microbiology and Biotechnology, Biology Faculty, Yerevan State University, Yerevan, 0025, Armenia.
Ani HarutyunyanDepartment of Biochemistry, Microbiology and Biotechnology, Biology Faculty, Yerevan State University, Yerevan, 0025, Armenia.
Mikayel GinovyanResearch Institute of Biology, Yerevan State University, Yerevan, 0025, Armenia.
Robin SchubertEuropean X-Ray Free-Electron Laser Facility GmbH, 22869, Schenefeld, Germany.
Sofiya AydinyanTallinn University of Technology, Tallinn, 19086, Estonia.
Karen TrchounianDepartment of Biochemistry, Microbiology and Biotechnology, Biology Faculty, Yerevan State University, Yerevan, 0025, Armenia.
Lilit GabrielyanDepartment of Biochemistry, Microbiology and Biotechnology, Biology Faculty, Yerevan State University, Yerevan, 0025, Armenia. lgabrielyan@ysu.am.
Liana GabrielyanDepartment of Physical and Colloids Chemistry, Chemistry Faculty, Yerevan State University, Yerevan, 0025, Armenia.

Funding

Higher Education and Science Committee of the Republic of Armenia 24WS-1F025
6 · The paper itself

Abstract

Novel approaches for producing silver nanoparticles (Ag-NPs), which are widely used in biomedicine, biotechnology, and agriculture, are of considerable importance. This study highlights a simple and cost-effective biological method for the synthesis of Ag-NPs using the leaf extract of the hydroponically cultivated Moringa oleifera (MOAg-NPs), alongside the analysis of the biosynthesized NPs. One of the advantages of hydroponic cultivation over traditional soil-based methods is that plants are cleaner since they are not in contact with soil and can be cultivated with fewer chemical inputs. For characterization of the biosynthesized MOAg-NPs various methods have been used, such as UV-visible (UV-Vis) spectroscopy, transmission electron microscopy (TEM), X-Ray diffraction (XRD), and Fourier transform infrared (FTIR) spectroscopy. UV-Vis analysis revealed a prominent peak at 465 nm, indicating the synthesis of MOAg-NPs. TEM analysis demonstrated a spherical shape of MOAg-NPs with an average diameter of 10.0 ± 6.0 nm. The XRD pattern displayed Ag peaks at 2θ values corresponding to (111), (200), (220) and (311) reflections. The antibacterial efficacy of MOAg-NPs was assessed against Gram-positive (Enterococcus hirae, Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli), revealing their antibacterial potential at low concentrations. The general inhibitory mechanism of MOAg-NPs focuses on the energy-dependent total and N, N'-dicyclohexylcarbodiimide (DCCD)-sensitive H

Indexed as

Anti-Bacterial AgentsMetal NanoparticlesMoringa oleiferaPlant ExtractsPlant LeavesSilverCell SurvivalEscherichia coliHumansMicrobial Sensitivity TestsSpectroscopy, Fourier Transform InfraredX-Ray DiffractionAnti-Bacterial AgentsPlant ExtractsSilverAntibacterial activityATPase activityCytotoxicityGreen synthesisMoringa oleifera (Lam.)Silver nanoparticles

Identifiers

PMID40360564
PMCPMC12075600

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.