Observational studyJournal of the American Heart Association2025
Enhancing Thrombolysis Times in Acute Ischemic Stroke With Regional Dashboards: Results From the Florida Stroke Registry.
Observational study in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
16 authors.
Funding
Abstract
backgroundReducing time to intravenous thrombolysis (IVT) is crucial for effective ischemic stroke treatment. Through grassroots efforts, the FSR (Florida Stroke Registry) developed regional dashboards (RDs) displaying reperfusion metrics within local Stroke Coalitions to improve acute stroke care quality. We sought to evaluate whether RD use is associated with faster IVT times and improved hospitalization outcomes.
methodsWe compared IVT-treated cases of ischemic stroke at FSR hospitals participating in the RD initiative versus nonparticipating hospitals from January 2016 to December 2023. Primary outcomes were door-to-treatment time <20 minutes and onset-to-treatment time <60 minutes. Secondary outcomes included intracerebral hemorrhage after IVT, discharge disposition, and in-hospital death. Logistic regression models, adjusted for calendar year, patient characteristics, and hospital factors, assessed the association between RD use and study outcomes.
resultsBy the end of the study period, 92 of 172 FSR hospitals (53.5%) were participating in stroke coalitions and using RDs. Among 32 320 IVT-treated cases (mean age, 69±15 years, 48.4% women), 10 666 (33.0%) were treated in RD-participating hospitals. RD participation was independently associated with door-to-treatment time <20 minutes (12.7% versus 7.3%; adjusted odds ratio, 1.48 [95% CI, 1.35-1.63]) and onset-to-treatment time <60 minutes (13.9% versus 9.0%; adjusted odds ratio, 1.63 [95% CI, 1.49-1.80]), as well as increased likelihood of being discharged directly to home (adjusted odds ratio, 1.15 [95% CI, 1.07-1.23]).
conclusionsThe implementation of the FSR RD initiative within stroke coalitions was associated with faster IVT times and higher likelihood of home discharge. This quality improvement initiative, adaptable to local needs, could emerge as a valuable tool for enhancing stroke systems of care.
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