Evidence map›Paper›PMID 40359998›Full record

ArticleGigaScience2025

New implementation of data standards for AI in oncology: Experience from the EuCanImage project.

Teresa García-Lezana, Maciej Bobowicz, Santiago Frid, Michael Rutherford, Mikel Recuero, Katrine Riklund, Aldar Cabrelles, Marlena Rygusik, Lauren Fromont, Roberto Francischello and 9 more

Abstract read
In one paragraph

Article in GigaScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Teresa García-LezanaCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain.ORCID 0000-0002-7863-6784
Maciej Bobowicz2nd Department of Radiology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0002-3608-1960
Santiago FridClinical Informatics Service, Hospital Clínic de Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-8400-5770
Michael RutherfordDepartment of Biomedical Informatics, University of Arkansas for Medical Sciences, 72205 Little Rock, Arkansas, United States.ORCID 0000-0003-2665-753X
Mikel RecueroSocial and Legal Sciences Applied to the New Technosciences Research Group, University of the Basque Country (UPV/EHU), 48940 Bilbao, Spain.ORCID 0000-0003-3813-8462
Katrine RiklundDepartment of DIagnostics and Intervention, Diagnostic Radiology, Umeå university, 90187 Umeå, Sweden.ORCID 0000-0001-5227-8117
Aldar CabrellesCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain.ORCID 0000-0002-1131-3139
Marlena Rygusik2nd Department of Radiology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0009-0003-6352-0927
Lauren FromontCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain.ORCID 0000-0002-2900-3868
Roberto FrancischelloAcademic Radiology, Department of Translational Research, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-4161-0193
Emanuele NeriAcademic Radiology, Department of Translational Research, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-7950-4559
Salvador CapellaBarcelona Supercomputing Center (BSC), 08034 Barcelona, Spain.ORCID 0000-0002-0309-604X
Arcadi NavarroCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain.
Fred PriorDepartment of Biomedical Informatics, University of Arkansas for Medical Sciences, 72205 Little Rock, Arkansas, United States.ORCID 0000-0002-6314-5683
Jonathan BonaDepartment of Biomedical Informatics, University of Arkansas for Medical Sciences, 72205 Little Rock, Arkansas, United States.ORCID 0000-0003-1402-9616
Pilar NicolasSocial and Legal Sciences Applied to the New Technosciences Research Group, University of the Basque Country (UPV/EHU), 48940 Bilbao, Spain.ORCID 0000-0003-4166-5941
Martijn P A StarmansDepartment of Radiology and Nuclear Medicine and Department of Pathology, Erasmus MC Medical Center, 3015 GD Rotterdam, the Netherlands.ORCID 0000-0001-5086-7153
Karim LekadirInstitució Catalana de Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Spain.ORCID 0000-0002-9456-1612
Jordi RamblaCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain.ORCID 0000-0001-9091-257X

Funding

Horizon 2020 952103
6 · The paper itself

Abstract

backgroundAn unprecedented amount of personal health data, with the potential to revolutionize precision medicine, is generated at health care institutions worldwide. The exploitation of such data using artificial intelligence (AI) relies on the ability to combine heterogeneous, multicentric, multimodal, and multiparametric data, as well as thoughtful representation of knowledge and data availability. Despite these possibilities, significant methodological challenges and ethicolegal constraints still impede the real-world implementation of data models. TECHNICAL DETAILS: The EuCanImage is an international consortium aimed at developing AI algorithms for precision medicine in oncology and enabling secondary use of the data based on necessary ethical approvals. The use of well-defined clinical data standards to allow interoperability was a central element within the initiative. The consortium is focused on 3 different cancer types and addresses 7 unmet clinical needs. We have conceived and implemented an innovative process to capture clinical data from hospitals, transform it into the newly developed EuCanImage data models, and then store the standardized data in permanent repositories. This new workflow combines recognized software (REDCap for data capture), data standards (FHIR for data structuring), and an existing repository (EGA for permanent data storage and sharing), with newly developed custom tools for data transformation and quality control purposes (ETL pipeline, QC scripts) to complement the gaps.

conclusionThis article synthesizes our experience and procedures for health care data interoperability, standardization, and reproducibility.

Indexed as

Artificial IntelligenceMedical OncologyNeoplasmsAlgorithmsHumansPrecision MedicineSoftwareartificial intelligencedata modelFHIRinteroperability

Identifiers

PMID40359998
PMCPMC12071370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.