ReviewInternational dental journal2025
Facts and Fallacies of the Fluoride Controversy: A Contemporary Perspective.
Review in International dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Cost-Effectiveness of Population-Level Fluoride Policies: A Systematic Review of Health and Economic Outcomes.International dental journal · 2026Pooled it
- Effects of Antibiotics and Anti-Inflammatory Drugs on Enamel Development: A Systematic Review with Quantitative Synthesis.International dental journal · 2026Pooled it
- The Use of Topical Fluoride for Caries Prevention.International dental journal · 2026Guideline
- Key virulence genes associated withFrontiers in oral health · 2025Pooled it
- Fluoride enamel stability and remineralization.Anatomy & cell biology · 2026Review
- On-demand caries prevention: on-site generated slightly acidic electrolyzed water as a potent and biocompatible anti- Streptococcus mutans agent.BMC oral health · 2026Article
- Effect of a 45S5 bioactive glass-containing gel on the remineralization of artificial caries-like lesions in primary teeth: an in vitro study.BMC oral health · 2026Article
- Human Enamel Formation: A Scoping Review for Oral Health Professionals.Dentistry journal · 2026Review
- Dental Morbidity Among School-Going Adolescents in a Fluoride-Endemic Belt of Rural Andhra Pradesh.Cureus · 2026Article
- Assessing links between dental fluorosis and oral/systemic health via salivary microbiome in Chinese young adults.International dental journal · 2026Article
- The Effect of Toothpaste Suspensions on the Formation of Oral Biofilms In Situ.International dental journal · 2026Article
- Contemporary Applications of Robotic Systems in Dental Implantology: A Review.International dental journal · 2026Review
- Effect of Topical Fluoride Application Temperature on Recharge and Rerelease in Different Restorative Materials.International dental journal · 2026Article
- Water fluoridation today: - benefits and challenges.Frontiers in oral health · 2026Review
- Fluoridation in Chile: historical context, current programs, challenges, and future directions.Frontiers in oral health · 2026Review
- Salivary Proteomic Signatures Reveal Novel Mechanistic Insights into Moderate Dental Fluorosis Pathogenesis and Oral Homeostasis Disruption.Computational and structural biotechnology journal · 2026Article
- Exploring artificial intelligence chatbots in pediatric fluoride education: a cross-sectional study.Scientific reports · 2025Article
- The metagenome and metabolome signatures of dental biofilms associated with severe dental fluorosis.Journal of oral microbiology · 2025Article
- Effect of particle size reduction on the physicochemical and mechanical properties of conventional glass ionomer cement.Frontiers in dental medicine · 2025Article
- Autism Spectrum Disorder: Nature vs. Nurture.Missouri medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluoride is a natural element recognized for its dental benefits. Fluoride prevents caries due to its antimicrobial activity, enhancing enamel resistance and promoting remineralization After decades of fluoridation of municipal water supplies to reduce dental caries, an intense debate has resurfaced regarding water fluoridation as a public health strategy to combat caries. This renewed discourse occurs against the backdrop of extensive data that clearly demonstrate the vital role of fluoride in caries prevention. Indeed, the Centres for Disease Control and Prevention has stated water fluoridation as one of the top ten public health interventions in the twentieth century. The FDI World Dental Federation also advocates systemic fluoride use as a cost-effective caries prevention strategy, and supports its inclusion in public health policies through a number of policy directives. This debate in the US has intensified as a Court concluded that water fluoridation poses unreasonable risks such as reduction of the intelligence quotient (IQ) in children. Additionally, recent statements from the leadership of the US Health and Human Services agency suggest that water fluoridation may cause more harm than good leading some states, like Utah, to revoke fluoridation mandates This article aims to provide a contemporary perspective on fluoride by revisiting its benefits, controversies, and potential risks. It highlights the dual role of fluoride in both individual oral care and public health and underscores the necessity for safe, equitable, and effective delivery strategies tailored to the needs of diverse populations, balancing its preventive advantages with potential health concerns. The review culminates with a summary of policy statements from the FDI World Dental Federation regarding the promotion of oral health through both systemic and topical fluoridation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.