Evidence map›Paper›PMID 40359067›Full record

ArticleEmerging infectious diseases2025

Integrating Genomic Data into Public Health Surveillance for Multidrug-Resistant Organisms, Washington, USA.

Laura Marcela Torres, Jared Johnson, Audrey Valentine, Audrey Brezak, Emily C Schneider, Marisa D'Angeli, Jennifer Morgan, Claire Brostrom-Smith, Chi N Hua, Michael Tran and 6 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Investigation of invasiveFrontiers in public health · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Laura Marcela Torres
Jared Johnson
Audrey Valentine
Audrey Brezak
Emily C Schneider
Marisa D'Angeli
Jennifer Morgan
Claire Brostrom-Smith
Chi N Hua
Michael Tran
Darren Lucas
Joenice Gonzalez De Leon
Drew MacKellar
Philip Dykema
Kelly J Kauber
Allison Black

Funding

NCEZID CDC HHS U01 CK000630
6 · The paper itself

Abstract

Mitigating antimicrobial resistance (AMR) is a public health priority to preserve antimicrobial treatment options. The Washington State Department of Health in Washington, USA, piloted a process to leverage longitudinal genomic surveillance on the basis of whole-genome sequencing (WGS) and a genomics-first cluster definition to enhance AMR surveillance. Here, we outline the approach to collaborative surveillance and describe the pilot using 6 carbapenemase-producing organism outbreaks of 3 species: Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. We also highlight how we applied the approach to an emerging outbreak. We found that genomic and epidemiologic data define highly congruent outbreaks. By layering genomic and epidemiologic data, we refined linkage hypotheses and addressed gaps in traditional epidemiologic surveillance. With the accessibility of WGS, public health agencies must leverage new approaches to modernize surveillance for communicable diseases.

Indexed as

Bacterial InfectionsDrug Resistance, Multiple, BacterialGenomicsPublic Health SurveillanceAcinetobacter baumanniiAnti-Bacterial AgentsDisease OutbreaksGenome, BacterialHumansKlebsiella pneumoniaePseudomonas aeruginosaWashingtonWhole Genome SequencingAnti-Bacterial AgentsAcinetobacter baumanniiAMRAMR surveillanceantimicrobial resistancebacteriabacterial outbreakbioinformaticsepidemiologygenomic clustergenomicsKlebsiella pneumoniaeMDROmultidrug resistancePseudomonas aeruginosaUnited StatesWashington

Identifiers

PMID40359067
PMCPMC12078550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.