Evidence map›Paper›PMID 40358922›Full record

ArticleJournal of applied clinical medical physics2025

Enhanced analysis of gating latency in 0.35T MR-linac through innovative time synchronization of a motion phantom and plastic scintillation detector.

Mateb Al Khalifa, Tianjun Ma, Haya Aljuaid, Siyong Kim, William Y Song

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mateb Al KhalifaDepartment of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID https://orcid.org/0000-0003-0627-8903
Tianjun MaDepartment of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.
Haya AljuaidDepartment of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.
Siyong KimDepartment of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID https://orcid.org/0000-0002-9173-7141
William Y SongDepartment of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID https://orcid.org/0009-0003-3196-2368

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to evaluate how different gantry angles, breathing rates (BPM), cine image speeds, and tracking algorithms affect beam on/off latency and the subsequent impact on target dose for a 0.35T MR-Linac with a 6 MV FFF beam. The investigation incorporates an image-based MRI4D modus QA motion phantom (MQA) and a measurement-based plastic scintillation detector (PSD).

methodsThe MQA's target was customized with an insertion for a 1 mm PSD from BluePhysics. Both the PSD and the MQA were simultaneously synchronized to the Linac to capture latency signals. A plan was created in the ViewRay TPS to deliver dose to the target at three gantry angles (0°, 120°, and 240°). Each gantry angle was evaluated at three breathing rates (10, 12, and 15 BPM). The study also examined two imaging speeds (4 and 8 FPS) and four tracking algorithms.

resultsAcross all configurations at 4 FPS, the overall mean beam-on latency was 0.339 ± 0.06 s from the PSD and 0.318 ± 0.06 s from the MQA, whereas at 8 FPS it was 0.630 ± 0.07 s (PSD) and 0.609 ± 0.07 s (MQA). Conversely, the overall mean beam-off latency at 4 FPS was 0.153 ± 0.03 s (PSD) and 0.124 ± 0.03 s (MQA), while at 8 FPS it was 0.121 ± 0.06 s (PSD) and 0.205 ± 0.04 s (MQA). The overall mean difference between gating and non-gating doses was an increase of 12.050 ± 9.2 cGy at 4 FPS and 14.044 ± 7.4 cGy at 8 FPS.

conclusionThis comprehensive study underscores the significant influence of gantry angle, breathing rate, cine imaging speed, and tracking algorithms on latency and dose delivery accuracy in a 0.35T MR-Linac.

Indexed as

AlgorithmsImage Processing, Computer-AssistedMagnetic Resonance ImagingParticle AcceleratorsPhantoms, ImagingPlasticsRadiotherapy Planning, Computer-AssistedScintillation CountingHumansMotionRadiotherapy DosageRadiotherapy, Intensity-ModulatedRespirationPlasticsbeam on/off latencydose per pulseMRgRTMR‐linacplastic scintillation detectorQA

Identifiers

PMID40358922
PMCPMC12256679

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.