Evidence map›Paper›PMID 40358891›Full record

ArticleSpine deformity2025

Development and validation of a pediatric spine surgical invasiveness index.

Vivien Chan, Adeesya Gausper, Andrew Chan-Tai-Kong, Andy M Liu, Suhas Etigunta, Justin K Scheer, Lindsay M Andras, David L Skaggs

Abstract readValidation Study
In one paragraph

Article in Spine deformity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Vivien ChanSpine Center, Cedars-Sinai Medical Center, 444 S San Vicente Blvd, Ste 900, Los Angeles, CA, 90048, USA. Vivien.Chan@cshs.org.ORCID http://orcid.org/0000-0002-4757-4939
Adeesya GausperSpine Center, Cedars-Sinai Medical Center, 444 S San Vicente Blvd, Ste 900, Los Angeles, CA, 90048, USA.
Andrew Chan-Tai-KongDivision of Neurosurgery, University of Alberta Hospital, Edmonton, Alberta, Canada.
Andy M LiuSpine Center, Cedars-Sinai Medical Center, 444 S San Vicente Blvd, Ste 900, Los Angeles, CA, 90048, USA.
Suhas EtiguntaSpine Center, Cedars-Sinai Medical Center, 444 S San Vicente Blvd, Ste 900, Los Angeles, CA, 90048, USA.
Justin K ScheerSpine Center, Cedars-Sinai Medical Center, 444 S San Vicente Blvd, Ste 900, Los Angeles, CA, 90048, USA.
Lindsay M AndrasJackie and Gene Autry Orthopedic Center, Children's Hospital Los Angeles, Los Angeles, CA, USA.
David L SkaggsSpine Center, Cedars-Sinai Medical Center, 444 S San Vicente Blvd, Ste 900, Los Angeles, CA, 90048, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurgical invasiveness indices have been used in adult spine surgery to characterize the invasiveness of complex procedures and for risk stratification. This has not been studied in the pediatric population. The purpose of this study was to develop and validate a surgical invasiveness index for pediatric spinal deformity surgery.

methodsThe National Surgical Quality Improvement Program (NSQIP) Pediatric database was queried between the years 2016-2022. Patients were included if they were <18 years of age, received posterior or anterior-posterior spinal fusion surgery, and had a diagnosis of spinal deformity. The study cohort was divided into a derivation cohort and a validation cohort. A multivariable linear regression analysis was performed to identify surgical components associated with operative time. Surgical components of interest included number of posterior fusion levels, number of anterior fusion levels, pelvic instrumentation, posterior column osteotomies, three-column osteotomies, and prior spinal deformity surgery. Statistically significant variables were used to establish a pediatric spinal deformity surgical invasiveness index. The score was assessed and validated using linear and logistic regression analysis and receiver operating characteristic curve analysis on operative time and allogeneic transfusion.

resultsThere were 37,658 patients included (Derivation cohort: 26,372; Validation cohort: 11,286). In the linear regression analysis, more posterior fusion levels (7-12 levels: 0.54, p<0.001;>12 levels: 1.40, p<0.001), anterior fusion 1-3 levels (2.42, p<0.001), anterior fusion ≥4 levels (2.93, p<0.001), pelvic instrumentation (0.79, p<0.001), and previous spinal deformity surgery (0.44, p<0.001) were associated with longer operative time. Each level of posterior column osteotomy (0.13, p<0.001) and three-column osteotomy (0.61, p<0.001) were associated with increased operative time. Points were assigned to each surgical component: 7-12 posterior fusion levels (4 pts), >12 posterior fusion levels (11 pts), anterior fusion 1-3 levels (19 pts), anterior fusion ≥4 levels (23 pts), pelvic instrumentation (6 pts), previous spinal deformity surgery (3 pts), posterior column osteotomy (1 pt per level), and three-column osteotomy (5 pts per level). In the derivation cohort, each point was associated with an increase in operative time by 0.13 hours (R

conclusionA pediatric spinal deformity surgical invasiveness index was created and predictive of prolonged operative time and allogeneic transfusion. This is the first quantitative tool to measure the extent of surgical interventions in pediatric spine surgery.

Indexed as

Spinal CurvaturesSpinal FusionSpineAdolescentChildChild, PreschoolFemaleHumansMaleOperative TimeOsteotomyRetrospective StudiesMorbidityMortalityPediatricRisk prognosticationRisk stratificationScoliosis

Identifiers

PMID40358891
PMCPMC12401766

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.