ArticleLasers in medical science2025
Molecular insights into the effects of laser-induced optical breakdown (LIOB) after 1064 nm picosecond laser irradiation using a novel melanocyte-containing 3D skin model.
Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Comparative Efficacy and Safety of 1064-nm Picosecond Laser and 1927-nm Fractional Thulium Laser for Atrophic Acne Scars in Asian Patients: A Prospective, Randomized, Split-Face Study.Lasers in surgery and medicine · 2026Trial
- Article
- The Molecular Exposome of Visible Age Reversal: From Organ-Skin Axes to Regenerative Aesthetics.Molecules (Basel, Switzerland) · 2026Review
- Comparison of the efficacy and safety of 755-nm picosecond alexandrite laser with diffractive lens array vs. fractional microneedle radiofrequency for the treatment of facial photoaging: a retrospective study.Frontiers in medicine · 2026Article
- Deciphering molecular responses to radiofrequency microneedling in a 3D human skin model: new insights and modulation by aftercare treatment.Frontiers in medicine · 2026Article
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Authors and funding
5 authors.
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Abstract
Picosecond lasers use a mechanism known as laser-induced optical breakdown (LIOB). However, the underlying molecular mechanisms are not yet fully understood. The aim of this study was to gain insights into the molecular effects of LIOB using novel melanocyte-containing 3D skin models. Since the threshold of LIOB depends on the melanin content of the skin, we established a new human 3D skin model comprising melanocytes. Irradiation was done with a diffractive optical elements (DOE-) assisted fractional 1064 nm Nd: YAG picosecond laser utilizing the energy setting of 0.2 J/cm
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