Trial reportClinical oral investigations2025
Effect of copaiba oil-resin on dental sensitivity control and color change after bleaching: A randomized clinical trial.
Trial report in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis randomized clinical trial evaluated a copaiba oil-based gel in controlling dental sensitivity (DS) and color change after dental bleaching. MATERIALS AND
methodsSeventy-five volunteers were randomized into three groups (n = 25): GC (placebo gel - negative control); GKF2% (gel of 5% potassium nitrate and 2% sodium fluoride - positive control); and GCO (copaiba oil gel). Three bleaching sessions were performed using 35% hydrogen peroxide (HP 35%), with 7-day intervals. The desensitizing gels were applied for 10 min in each group. The DS was evaluated over 21 days using a visual analog scale (VAS). Color evaluation was done with a spectrophotometer before and after bleaching using the CIEDE2000. The DS was assessed between groups (Kruskal-Wallis test) and within groups (Friedman test). The color change was analyzed using one-way ANOVA and Tukey's test.
resultsGCO and GKF2% showed the lowest sensitivity values, with no significant difference (p < 0.05). In the intragroup analysis, GCO and GKF2% showed no differences across the three whitening sessions (p = 0.974, p = 0.213, p = 0.143, respectively). Conversely, GC exhibited an increase in DS after the last session (p = 0.035). All groups showed color change, without statistically significant differences between the groups (p = 0.725).
conclusionThe copaiba gel reduced dental sensitivity after treatment with 35% hydrogen peroxide, without affecting the bleaching effectiveness. CLINICAL RELEVANCE: The topical application of the experimental copaiba oil gel was effective in reducing dental sensitivity after bleaching with 35% hydrogen peroxide.
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