ArticleEchocardiography (Mount Kisco, N.Y.)2025
Safety and Feasibility of Early Targeted Neonatal Echocardiography and a Focused Assessment Protocol in Neonates With Congenital Diaphragmatic Hernia.
Article in Echocardiography (Mount Kisco, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Hemodynamic Phenotypes in Congenital Diaphragmatic Hernia: Unresolved Questions and Future Directions.Children (Basel, Switzerland) · 2026Article
- A hemodynamic-driven approach to chronic pulmonary hypertension in congenital diaphragmatic hernia.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Cardiac function in children with congenital diaphragmatic hernia: cardiac strain at birth and at 2-5 weeks of age.Frontiers in pediatrics · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCongenital diaphragmatic hernia (CDH) is a complex disease with significant morbidity and mortality. The use of echocardiography, traditionally a pediatric cardiology echocardiogram (PCE), has significantly advanced the management of CDH but its availability can be limited, and there are concerns regarding clinical stability during the assessment. Neonatologist-performed targeted neonatal echocardiography (TNE) has been proposed as a supplementary modality in CDH. Herein, we evaluate the feasibility and safety of integrating early TNE and a focused assessment protocol in CDH care.
methodsThis was a retrospective, single-center study of neonates with CDH who received either an initial PCE (n = 26) or complete TNE (n = 20). The timing, images, and duration of the study were collected, as well as clinical stability data. A focused TNE protocol for cases of clinical instability was similarly evaluated.
resultsDespite similar clinical risk predictors, TNE was performed sooner (mean 3.0 vs. 11.6 h, p < 0.0001) and quicker (mean 25.9 vs. 44.4 min, p = 0.0001) than a PCE. While fewer images were obtained (mean 102.0 vs. 143.2 images, p < 0.0001), no cases of congenital heart disease were missed. TNE and PCE were equally well tolerated. When indicated, a focused TNE protocol was utilized that provided actionable information with a mean duration of 7.2 min (n = 4).
conclusionTNE can be performed early, quickly, and safely in neonates with CDH. A focused TNE protocol may be useful even in non-TNE centers for the acute care of critically ill neonates with CDH.
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